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. 2024 May 22;16(11):1572.
doi: 10.3390/nu16111572.

The Influence of Vitamin D Levels on Dental Caries: A Retrospective Study of the United States Population

Man Hung  1   2   3   4 , Himani Patel  1 , Samantha Lee  1 , Justin Nguyen  1 , Amir Mohajeri  1
Affiliations

The Influence of Vitamin D Levels on Dental Caries: A Retrospective Study of the United States Population

Man Hung et al. Nutrients. .

Abstract

(1) Background: This study examines vitamin D's impact on dental caries to inform prevention strategies, given its critical role in bone and calcium regulation, vital for dental health. (2) Methods: Data from 18,683 participants of the National Health and Nutrition Examination Survey (NHANES) 2011-2016 were analyzed. NHANES collects U.S. population data through interviews, physical exams, and tests, including vitamin D levels and dental health assessed using both the decayed, missing, and filled teeth (DMFT) index and the presence of untreated dental caries. Vitamin D levels were measured according to serum 25(OH)D concentrations, and the analyses adjusted for confounders such as body mass index (BMI) and socioeconomic status (SES) using Chi-square, Mann-Whitney U, Kruskal-Wallis tests, as well as logistic and Poisson regression. (3) Results: This study found a mean DMFT score of 7.36 and a 33.2% prevalence of untreated dental caries. A higher caries prevalence was correlated with a lower SES (p < 0.001), the male gender (p < 0.001), and a higher BMI (p < 0.001). Severe vitamin D deficiency (<25 nmol/L) doubled the risk of dental caries, with odds ratios of 2.261 and 1.953 after adjusting for demographic factors and BMI. (4) Conclusions: Our study confirms a significant relationship between low vitamin D levels and an increased risk of dental caries nationwide, even after accounting for sociodemographic factors, emphasizing the importance of maintaining sufficient vitamin D levels for preventing caries.

Keywords: NHANES; dental caries; dental health; oral health; socioeconomic factors; vitamin D; vitamin D deficiency.

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Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Institute of Medicine of the National Academies. Committee to Review Dietary Reference Intakes for Vitamin D and Calcium . In: DRI Dietary Reference Intakes Calcium Vitamin D. Ross A.C., Taylor C.L., Yaktine A.L., Del Valle H.B., editors. National Academies Press; Washington, DC, USA: 2011. [(accessed on 10 June 2023)]. Available online: https://nap.nationalacademies.org/read/13050/chapter/1.
    1. Holick M.F. Resurrection of vitamin D deficiency and rickets. J. Clin. Investig. 2006;116:2062–2072. doi: 10.1172/JCI29449. - DOI - PMC - PubMed
    1. Khazai N., Judd S.E., Tangpricha V. Calcium and vitamin D: Skeletal and extraskeletal health. Curr. Rheumatol. Rep. 2008;10:110–117. doi: 10.1007/s11926-008-0020-y. - DOI - PMC - PubMed
    1. National Institute of Dental and Craniofacial Research Dental Caries (Tooth Decay) [(accessed on 18 April 2024)]; Available online: https://www.nidcr.nih.gov/research/data-statistics/dental-caries#.
    1. Selwitz R.H., Ismail A.I., Pitts N.B. Dental caries. Lancet. 2007;369:51–59. doi: 10.1016/S0140-6736(07)60031-2. - DOI - PubMed

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