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Randomized Controlled Trial
. 2024 May 29;16(11):1685.
doi: 10.3390/nu16111685.

The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial

Ayesha S Al Dhaheri  1 , Dana Hasan Alkhatib  1 , Jack Feehan  2 , Leila Cheikh Ismail  3   4 , Vasso Apostolopoulos  2   5 , Lily Stojanovska  1   2
Affiliations
Randomized Controlled Trial

The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial

Ayesha S Al Dhaheri et al. Nutrients. .

Erratum in

Abstract

Non-communicable diseases (NCDs) place a significant burden on global health and the healthcare systems which support it. Metabolic syndrome is a major risk factor for a large number of NCDs; however, treatments remain limited. Previous research has shown the protective benefits of edible dietary spices on key components of metabolic syndrome. Therefore we performed a 12-week double-blind, placebo-controlled, randomized, clinical trial to evaluate the effect of ginger (Zingiber officinale), cinnamon (Cinnamomum), and black seed (Nigella sativa) consumption on blood glucose, lipid profiles, and body composition in 120 participants with, or at risk of, metabolic syndrome. Each participant consumed 3 g/day of powder (spice or placebo). Data related to different parameters were collected from participants at the baseline, midpoint, and endpoint of the intervention. Over the 12-week interventions, there was an improvement in a number of biochemical indices of metabolic syndrome, including fasting blood glucose, HbA1c, LCL, and total cholesterol associated with supplementation with the spices when compared to a placebo. This study provides evidence to support the adjunct use of supplementation for those at risk of metabolic syndrome and its sequelae.

Keywords: black seed; cinnamon; dyslipidemia; edible spices; ginger; hyperglycemia; hypertension; metabolic syndrome.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Screening criteria for metabolic syndrome in the study. M: Male, F: Female.
Figure 2
Figure 2
Participant screening and inclusion.
Figure 3
Figure 3
Recruitment and participant dropout.
See this image and copyright information in PMC

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