Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours
- PMID: 38892731
- PMCID: PMC11173254
- DOI: 10.3390/jcm13113020
Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours
Abstract
The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.
Keywords: head and neck cancer; oligometastatic; recurrent; reirradiation; stereotactic body radiotherapy.
Conflict of interest statement
The authors declare no conflicts of interest.
Similar articles
-
Reirradiation of head and neck cancer using modern highly conformal techniques.Head Neck. 2018 Sep;40(9):2078-2093. doi: 10.1002/hed.25180. Epub 2018 Apr 23. Head Neck. 2018. PMID: 29684256 Review.
-
Adjuvant stereotactic body radiotherapy±cetuximab following salvage surgery in previously irradiated head and neck cancer.Laryngoscope. 2014 Jul;124(7):1579-84. doi: 10.1002/lary.24441. Epub 2014 Apr 22. Laryngoscope. 2014. PMID: 24123056
-
Stereotactic Body Radiotherapy for Recurrent Unresectable Head and Neck Cancers.Cancer Control. 2016 Jan;23(1):6-11. doi: 10.1177/107327481602300103. Cancer Control. 2016. PMID: 27009451 Review.
-
Stereotactic Pelvic Reirradiation for Locoregional Cancer Relapse.Clin Oncol (R Coll Radiol). 2021 Jan;33(1):e15-e21. doi: 10.1016/j.clon.2020.06.009. Epub 2020 Jul 5. Clin Oncol (R Coll Radiol). 2021. PMID: 32641243
-
Reirradiation using stereotactic body radiotherapy in the management of recurrent or second primary head and neck cancer: A meta-analysis and systematic review.Oral Oncol. 2020 Aug;107:104757. doi: 10.1016/j.oraloncology.2020.104757. Epub 2020 May 7. Oral Oncol. 2020. PMID: 32388412
References
-
- Brockstein B., Haraf D.J., Rademaker A.W., Kies M.S., Stenson K.M., Rosen F., Mittal B.B., Pelzer H., Fung B.B., Witt M.E., et al. Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: A 9-year, 337-patient, multi-institutional experience. Ann. Oncol. 2004;15:1179–1186. doi: 10.1093/annonc/mdh308. - DOI - PubMed
-
- Cooper J.S., Zhang Q., Pajak T.F., Forastiere A.A., Jacobs J., Saxman S.B., Kish J.A., Kim H.E., Cmelak A.J., Rotman M., et al. Long-term follow-up of the RTOG 9501/intergroup phase III trial: Postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 2012;84:1198–1205. doi: 10.1016/j.ijrobp.2012.05.008. - DOI - PMC - PubMed
-
- Dawson L.A., Anzai Y., Marsh L., Martel M.K., Paulino A., Ship J.A., Eisbruch A. Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys. 2000;46:1117–1126. doi: 10.1016/s0360-3016(99)00550-7. - DOI - PubMed
Publication types
LinkOut - more resources
Full Text Sources