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Review
. 2024 Jun 1;14(11):1172.
doi: 10.3390/diagnostics14111172.

Struma Ovarii during Pregnancy

Affiliations
Review

Struma Ovarii during Pregnancy

Gabriela Dumachița-Șargu et al. Diagnostics (Basel). .

Abstract

Struma ovarii is a rare type of ovarian teratoma primarily composed of over 50% thyroid tissue. Its occurrence is reported in 2-5% of all ovarian teratomas, with approximately 0.5% to 10% showing malignant transformation. Managing it during pregnancy poses significant challenges as pregnancy can promote the growth of malignant struma ovarii due to elevated levels of ovarian and pregnancy-related hormones, including estrogen, progesterone, and human chorionic gonadotrophin (hCG). Most ovarian tumors, including struma ovarii, are detected during routine ultrasonography in the first and second trimesters, often as acute emergencies. Diagnosis during pregnancy is rare, with some cases incidentally discovered during cesarean section when inspecting the adnexa for ovarian cysts. This review explores the diagnostic, management, and therapeutic approaches to struma ovarii during pregnancy.

Keywords: pregnancy; struma ovarii; thyroid carcinoma.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Struma ovarii in pregnancy appearing as a non specific multilocular solid tumor with two areas of “struma pearls”.
Figure 2
Figure 2
Solid tumor, with white surface.
Figure 3
Figure 3
Struma ovarii, gelatinous, red–brown on cut surface.
Figure 4
Figure 4
Different-sized thyroid follicles within struma ovarii, HE × 10.
Figure 5
Figure 5
Different-sized thyroid follicles within struma ovarii, predominantly cystic, residual corpus albicans, HE × 10.
Figure 6
Figure 6
Intraoperatory view. Struma ovarii.

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