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Editorial
. 2024 Jun 6;12(16):2698-2700.
doi: 10.12998/wjcc.v12.i16.2698.

Metabolic dynamics in chronic gastritis: Examining urinary profiles post Helicobacter pylori eradication

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Editorial

Metabolic dynamics in chronic gastritis: Examining urinary profiles post Helicobacter pylori eradication

Imshaal Musharaf et al. World J Clin Cases. .

Abstract

Chronic gastritis is the persistent and insidious inflammation of the gastric lining. Helicobacter pylori (H. pylori) has been identified as the most common cause of chronic gastritis and consequently elimination of H. pylori can lead to its cure. This editorial explores the use of urinary metabolic profiles before and after eradication to identify biomarkers that can aid in prognosis and treatment. Despite providing promising insights, there are limitations such as a small sample size (17 patients), a narrow treatment period of 2 wk, and treatment heterogeneity, which raise concerns. Nevertheless, these findings have opened a gateway to enhancing the treatment and prognosis of chronic gastritis through urinary metabolomics.

Keywords: Chronic gastritis; Gastritis; Helicobacter pylori; Precancerous lesions; Quadruple therapy; Urine metabolomics.

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Conflict of interest statement

Conflict-of-interest statement: All the authors declare that they have no conflict of interest.

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References

    1. Watari J, Chen N, Amenta PS, Fukui H, Oshima T, Tomita T, Miwa H, Lim KJ, Das KM. Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development. World J Gastroenterol. 2014;20:5461–5473. - PMC - PubMed
    1. Sipponen P, Maaroos HI. Chronic gastritis. Scand J Gastroenterol. 2015;50:657–667. - PMC - PubMed
    1. Haenszel W, Correa P, López A, Cuello C, Zarama G, Zavala D, Fontham E. Serum micronutrient levels in relation to gastric pathology. Int J Cancer. 1985;36:43–48. - PubMed
    1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74–108. - PubMed
    1. Clish CB. Metabolomics: an emerging but powerful tool for precision medicine. Cold Spring Harb Mol Case Stud. 2015;1:a000588. - PMC - PubMed

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