Metabolic dynamics in chronic gastritis: Examining urinary profiles post Helicobacter pylori eradication
- PMID: 38899295
- PMCID: PMC11185323
- DOI: 10.12998/wjcc.v12.i16.2698
Metabolic dynamics in chronic gastritis: Examining urinary profiles post Helicobacter pylori eradication
Abstract
Chronic gastritis is the persistent and insidious inflammation of the gastric lining. Helicobacter pylori (H. pylori) has been identified as the most common cause of chronic gastritis and consequently elimination of H. pylori can lead to its cure. This editorial explores the use of urinary metabolic profiles before and after eradication to identify biomarkers that can aid in prognosis and treatment. Despite providing promising insights, there are limitations such as a small sample size (17 patients), a narrow treatment period of 2 wk, and treatment heterogeneity, which raise concerns. Nevertheless, these findings have opened a gateway to enhancing the treatment and prognosis of chronic gastritis through urinary metabolomics.
Keywords: Chronic gastritis; Gastritis; Helicobacter pylori; Precancerous lesions; Quadruple therapy; Urine metabolomics.
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Conflict of interest statement
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Similar articles
-
Urinary metabolic profiles during Helicobacter pylori eradication in chronic gastritis.World J Clin Cases. 2024 Feb 16;12(5):951-965. doi: 10.12998/wjcc.v12.i5.951. World J Clin Cases. 2024. PMID: 38414611 Free PMC article.
-
Ten-day bismuth-containing quadruple therapy is effective as first-line therapy for Helicobacter pylori-related chronic gastritis: a prospective randomized study in China.Clin Microbiol Infect. 2017 Jun;23(6):391-395. doi: 10.1016/j.cmi.2016.12.032. Epub 2017 Jan 7. Clin Microbiol Infect. 2017. PMID: 28077338 Clinical Trial.
-
[The effect of Helicobacter pylori eradication on chronic gastritis].Nihon Rinsho. 2013 Aug;71(8):1442-8. Nihon Rinsho. 2013. PMID: 23967677 Review. Japanese.
-
[Quadruple regimens using domestically manufactured drugs in gastritis and duodenal ulcer patients for Helicobacter pylori eradication: a perspective, multicenter, randomized controlled trial].Zhonghua Yi Xue Za Zhi. 2016 Jan 26;96(4):260-4. doi: 10.3760/cma.j.issn.0376-2491.2016.04.006. Zhonghua Yi Xue Za Zhi. 2016. PMID: 26879784 Clinical Trial. Chinese.
-
Future candidates for indications of Helicobacter pylori eradication: do the indications need to be revised?J Gastroenterol Hepatol. 2012 Feb;27(2):200-11. doi: 10.1111/j.1440-1746.2011.06961.x. J Gastroenterol Hepatol. 2012. PMID: 22098099 Review.
References
Publication types
LinkOut - more resources
Full Text Sources