Metabolic dynamics in chronic gastritis: Examining urinary profiles post Helicobacter pylori eradication
- PMID: 38899295
- PMCID: PMC11185323
- DOI: 10.12998/wjcc.v12.i16.2698
Metabolic dynamics in chronic gastritis: Examining urinary profiles post Helicobacter pylori eradication
Abstract
Chronic gastritis is the persistent and insidious inflammation of the gastric lining. Helicobacter pylori (H. pylori) has been identified as the most common cause of chronic gastritis and consequently elimination of H. pylori can lead to its cure. This editorial explores the use of urinary metabolic profiles before and after eradication to identify biomarkers that can aid in prognosis and treatment. Despite providing promising insights, there are limitations such as a small sample size (17 patients), a narrow treatment period of 2 wk, and treatment heterogeneity, which raise concerns. Nevertheless, these findings have opened a gateway to enhancing the treatment and prognosis of chronic gastritis through urinary metabolomics.
Keywords: Chronic gastritis; Gastritis; Helicobacter pylori; Precancerous lesions; Quadruple therapy; Urine metabolomics.
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Conflict of interest statement
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
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