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Review
. 2024 Jun 6:11:1407182.
doi: 10.3389/fnut.2024.1407182. eCollection 2024.

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Fangyu Guo #  1   2 , Chunhai Li #  3 , Jiaxin Dou  1   2 , Jie Liang  1   2 , Zouquan Chen  1   2 , Zhenshang Xu  1   2 , Ting Wang  1   2
Affiliations
Review

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Fangyu Guo et al. Front Nutr. .

Abstract

Scutellaria baicalensis Georgi is a medicinal herb with a rich history of use in traditional Chinese medicine. This review concentrates on the chemical constituents of Scutellaria baicalensis Georgi, with a particular emphasis on flavonoids such as baicalin, baicalein, and wogonin. Additionally, it examines the effects of probiotic fermentation on the plant's chemical profile and pharmacological actions. Evidence suggests that probiotic fermentation markedly modifies the bioactive components of Scutellaria baicalensis Georgi, thereby augmenting its medicinal potency. The paper delves into the mechanisms by which the primary active constituents of Scutellaria baicalensis Georgi are altered during fermentation and how these changes influence its pharmacological properties. This review aims to lay a theoretical groundwork for the clinical utilization of Scutellaria baicalensis Georgi and the formulation of innovative therapeutic approaches.

Keywords: Scutellaria baicalensis Georgi; application; fermentation; pharmacological properties; probiotics.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The function of Scutellaria baicalensis Georgi.
Figure 2
Figure 2
The medicinal plant Scutellaria baicalensis Georgi. (A) Baicalin; (B) baicalein; (D) wogonin.
Figure 3
Figure 3
Advantages of traditional Chinese medicine fermented by probiotic.
Figure 4
Figure 4
Baicalin transformation structure.
See this image and copyright information in PMC

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