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Review
. 2024 Jun 21;316(7):419.
doi: 10.1007/s00403-024-03179-7.

Diagnostic accuracy of high-frequency ultrasound for cutaneous neoplasms: a narrative review of the literature

Catherine Grace P Hobayan  1 , Ashley N Gray  2 , Margo F Waters  1 , Layna A Mager  1 , Sonja Kobayashi  1 , Ellen W Essien  1 , Catherine A Ulman  2 , Benjamin H Kaffenberger  3
Affiliations
Review

Diagnostic accuracy of high-frequency ultrasound for cutaneous neoplasms: a narrative review of the literature

Catherine Grace P Hobayan et al. Arch Dermatol Res. .

Abstract

High-frequency ultrasound has been used to visualize depth and vascularization of cutaneous neoplasms, but little has been synthesized as a review for a robust level of evidence about the diagnostic accuracy of high-frequency ultrasound in dermatology. A narrative review of the PubMed database was performed to establish the correlation between ultrasound findings and histopathologic/dermoscopic findings for cutaneous neoplasms. Articles were divided into the following four categories: melanocytic, keratinocytic/epidermal, appendageal, and soft tissue/neural neoplasms. Review of the literature revealed that ultrasound findings and histopathology findings were strongly correlated regarding the depth of a cutaneous neoplasm. Morphological characteristics were correlated primarily in soft tissue/neural neoplasms. Overall, there is a paucity of literature on the correlation between high-frequency ultrasound and histopathology of cutaneous neoplasms. Further studies are needed to investigate this correlation in various dermatologic conditions.

Keywords: Cutaneous neoplasm; General dermatology; Medical dermatology; Oncology; Pathology; Ultrasound.

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Conflict of interest statement

The authors declare no competing interests.

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References

    1. Wortsman X (2021) Practical applications of ultrasound in dermatology. Clin Dermatol 39(4):605–623. 10.1016/j.clindermatol.2021.03.007 10.1016/j.clindermatol.2021.03.007 - DOI - PubMed
    1. Catalano O, Roldán FA, Varelli C, Bard R, Corvino A, Wortsman X (2019) Skin cancer: findings and role of high-resolution ultrasound. J Ultrasound 22(4):423–431. 10.1007/s40477-019-00379-0 10.1007/s40477-019-00379-0 - DOI - PMC - PubMed
    1. Chaput L, Laurent E, Pare A et al (2018) One-step surgical removal of cutaneous melanoma with surgical margins based on preoperative ultrasound measurement of the thickness of the melanoma. Eur J Dermatol EJD 28(2):202–208. 10.1684/ejd.2018.3298 10.1684/ejd.2018.3298 - DOI - PubMed
    1. Hayashi K, Koga H, Uhara H, Saida T (2009) High-frequency 30-MHz sonography in preoperative assessment of tumor thickness of primary melanoma: usefulness in determination of surgical margin and indication for sentinel lymph node biopsy. Int J Clin Oncol 14(5):426–430. 10.1007/s10147-009-0894-3 10.1007/s10147-009-0894-3 - DOI - PubMed
    1. Hoffmann K, Jung J, el Gammal S, Altmeyer P (1992) Malignant melanoma in 20-MHz B scan sonography. Dermatol Basel Switz 185(1):49–55. 10.1159/00024740310.1159/000247403 - DOI - PubMed