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Review
. 2024 Aug:286-287:18-24.
doi: 10.1016/j.cancergen.2024.06.002. Epub 2024 Jun 17.

Cancer treatments: Past, present, and future

Dmitriy Sonkin  1 , Anish Thomas  2 , Beverly A Teicher  3
Affiliations
Review

Cancer treatments: Past, present, and future

Dmitriy Sonkin et al. Cancer Genet. 2024 Aug.

Abstract

There is a rich history of cancer treatments which provides a number of important lessons for present and future cancer therapies. We outline this history by looking in the past, reviewing the current landscape of cancer treatments, and by glancing at the potential future cancer therapies.

Keywords: ADC; BiTE; CART; Cancer; Cancer genetics; Cancer therapy; Cancer treatment; Cancer treatments history; Chemotherapy; Immunology; Oncology; Radiation therapy; Targeted therapy.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no conflict of interest.

Figures

Figure 1.
Figure 1.
Trends in better cancer models and more targeted cancer treatments.
Figure 2.
Figure 2.
Using somatic mutations as targets for insertion of sequences coding for peptides known to trigger immune response due to previous routine vaccinations.
See this image and copyright information in PMC

References

    1. Cole MP, Jones CT & Todd ID A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474. Br. J. Cancer 25, 270–275 (1971). - PMC - PubMed
    1. Hanahan D & Weinberg RA Hallmarks of Cancer: The Next Generation. Cell 144, 646–674 (2011). - PubMed
    1. Wyld L, Audisio RA & Poston GJ The evolution of cancer surgery and future perspectives. Nat. Rev. Clin. Oncol 12, 115–124 (2015). - PubMed
    1. Crosby D et al. Early detection of cancer. Science 375, eaay9040 (2022). - PubMed
    1. Lederman M The early history of radiotherapy: 1895–1939. Int. J. Radiat. Oncol 7, 639–648 (1981). - PubMed