Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jun 24;40(2):73-77.
doi: 10.2478/immunohematology-2024-011. eCollection 2024 Jun 1.

How anti-c in a D- patient prompted lifesaving work between a transfusion service and a blood center reference laboratory

Gavin Patch  1 , Joan Maurer  2 , Arun Sendilnathan  3 , Christine Leak  3 , Elizabeth Nartowicz  1 , Victoria Kavitsky  2 , Dexter Facey  2 , Sandra T Nance  2 , Margaret A Keller  2
Affiliations

How anti-c in a D- patient prompted lifesaving work between a transfusion service and a blood center reference laboratory

Gavin Patch et al. Immunohematology. .

Abstract

This case report showcases an extraordinary collaboration to support the transfusion needs of a patient with a rare phenotype and long-standing anemia due to gastrointestinal bleeding. This report describes the Immunohematology Reference Laboratory testing and logistics of rare blood provision over an 11-year period, as well as a summary of the hematologic, gastroenterologic, and surgical interventions. This case illustrates how a strong collaboration among the clinical team, laboratory, blood center, and the rare donor community facilitated successful management of this patient's anemia until the patient could receive life-changing treatment.

Keywords: American Rare Donor Program; rare blood; red blood cell alloimmunization.

PubMed Disclaimer

References

    1. Nance S, Arndt P, Garratty G. Predicting the clinical significance of red cell alloantibodies using a monocyte monolayer assay. Transfusion 1987;27:449–52.
    1. Meny GM, Flickinger C, Marcucci CJ. The American Rare Donor Program. Crit Care 2013;28:110.e9–18. doi:10.1016/j.jcrc.2012.02.017.
    1. Keller MA, Nance ST, Kavitsky V et al. The American Rare Donor Program: twenty-five years supporting rare blood needs. Immunohematology In press.
    1. Maurer J, Nance S, Kavitsky V, Facey D, Keller M. High prevalence antigen negative unit requests: what if it includes being O negative? Transfusion 2021;35(Suppl 3):159–60A.
    1. Maurer J, Nance S, Kavitsky V, Facey D, Keller M . When rare blood goes overseas. Transfusion 2021;35(Suppl 3):80A.

LinkOut - more resources