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Review
. 2024 May;53(5):1033-1046.
doi: 10.18502/ijph.v53i5.15583.

Exposure to Mercury in the Air and Its Effect on Cardiovascular Diseases (CVD): A Systematic Review

Abdolkazem Neisi  1   2 , Fatemeh Koshki Nasab  3 , Arefeh Sepahvand  4 , Bita Falahi  5 , Masoume Taherian  6 , Ali Farhadi  4 , Parisa Asban  6 , Nastaran Tale Pour  2 , Majid Farhadi  3 , Abdollah Dargahi  7   8
Affiliations
Review

Exposure to Mercury in the Air and Its Effect on Cardiovascular Diseases (CVD): A Systematic Review

Abdolkazem Neisi et al. Iran J Public Health. 2024 May.

Abstract

Background: We aimed to verify the exposure to mercury in the air and its effect on cardiovascular disorders.

Methods: The review was conducted using PubMed, Scopus, Web of Science, Embase, and national databases (such as SID) from 1995-2022.

Results: Mercury exposure can cause many disorders in humans, including neurodevelopmental disorders in fetuses and children, adverse cardiovascular outcomes, hypertension, and diabetes. Mercury is a human neurotoxin, and in recent years its potentially harmful effects on cardiovascular disease (CVD) have raised concerns, mainly due to mercury's role in reducing oxidative stress.

Conclusion: Possible mechanisms of mercury toxicity in CVD include mercury-selenium interaction, increased lipid peroxidation, and oxidative stress. In this article, we review studies that have investigated the relationship between mercury and CVD.

Keywords: Cardiovascular disease; Exposure; Mercury; Risk factors.

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Figures

Fig. 1:
Fig. 1:
Representation of the search strategy based on PRISMA flow diagram
Fig. 2:
Fig. 2:
Sources of anthropogenic mercury emissions (Originl)
Fig. 3:
Fig. 3:
Natural sources of mercury emission (Original)
Fig. 4:
Fig. 4:
Mechanism of effect of mercury on cardiovascular disease (Original)
See this image and copyright information in PMC

References

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