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. 1985 May;21(5):607-13.
doi: 10.1016/0277-5379(85)90089-6.

Massive chemotherapy with non-frozen autologous bone marrow transplantation in 13 cases of refractory Hodgkin's disease

A M Carella, G Santini, A Santoro, P Coser, F Frassoni, M Martinengo, S Nati, A Congiu, D Giordano, R Cerri, et al.

Massive chemotherapy with non-frozen autologous bone marrow transplantation in 13 cases of refractory Hodgkin's disease

A M Carella et al. Eur J Cancer Clin Oncol. 1985 May.

Abstract

A group of 13 patients with advanced, diffuse Hodgkin's disease, poorly responding to the most widely employed primary chemotherapy regimens, were treated with massive chemotherapy (MCH) followed by rescue with non-frozen autologous bone marrow infusion (ABMT). Complete remission (CR) was obtained in 8/13 patients (61.5%) and partial remission in two. Hematopoietic recovery occurred in 12 cases. These preliminary results would seem to indicate that MCH with non-frozen ABMT may be successfully used in patients with resistant or relapsed Hodgkin's disease.

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