Toloese Generates Nitric Oxide through Natural Radiation of Far Infrared Rays, Reducing Serum Glucose, Cholesterol, and Triglycerides

Abstract

Toloese, a bed composition, is formulated with a combination of minerals of various wavelengths by utilizing a specific ratio and particle size. A maturation mixing technique is used without additional compression processes, resulting in the natural formation of numerous fine pores in the bed structure. At 40 °C, far infrared radiation in the range of 5-20 μm is emitted with a 0.916 radiant ratio, and the measured emitted radiant energy is 3.69 × 10² W/m²·μm. This study aimed to investigate the influence of far infrared radiation emitted from a Toloese bed on endogenous nitric oxide production. Clinical trials were conducted with 20 healthy adults aged 20 years. Blood samples were collected before and after Toloese bed usage for 1 h daily for 3 weeks. Nitric oxide levels in the saliva and blood of men and women significant increased after they used the Toloese bed for 1 h. Additionally, sweating sharply increased in the upper and lower body regions after Toloese bed usage. No hematological changes or adverse effects were observed, but blood glucose, cholesterol, and triglycerides decreased after Toloese bed usage compared with those before Toloese bed usage. These findings demonstrated that far infrared radiation emitted by the Toloese bed induced endogenous nitric oxide production and contributed to significant reductions in blood glucose, cholesterol, and triglyceride levels.

Keywords: Toloese; far infrared ray; nitric oxide.

Figure 1

Structure of the Toloese bed. (a) Schematic diagram, and (b) actual photo of the Toloese bed. The size of the Toloese plate is 840 mm × 1750 mm (width × length).

Figure 2

Changes and increased rates of salivary NO before and after using a Toloese bed. For three weeks, 1 h each day, a Toloese Bed at 37 °C was used. (a,b) represent the changes in salivary NO in males and females, respectively. (c,d) represent the increase rates of salivary NO after usage compared with pre-usage levels at week 0 in males and females, respectively. Values were expressed as mean ± standard deviation. n.s., non-significant. Paired t-tests were used to compare pre- and post-exposure measurements for each week, and one-way ANOVA was used to compare the pre-exposure measurements at week 0 with the post-exposure measurements for each subsequent week. * p < 0.05; ** p < 0.01.

Figure 3

Changes and increased rates of serum NO before and after using a Toloese bed. (a,b) represent the changes in serum NO in males and females, respectively. (c,d) represent the increase rates of serum NO after usage compared with pre-usage levels at week 0 in males and females, respectively. Values were expressed as mean ± standard deviation. n.s., non-significant. Paired t-tests were used to compare pre- and post-exposure measurements for each week, and one-way ANOVA was used to compare the pre-exposure measurements at week 0 with the post-exposure measurements for each subsequent week. * p < 0.05; ** p < 0.01; *** p < 0.001.

Figure 4

Changes in the sweat rate of the upper and lower body of (a) males and (b) females after Toloese bed usage in each week. Red indicates a high amount of sweat. Orange indicates a fairly high amount of sweat. Yellow indicates a moderate amount of sweat. Light green indicates a slight amount of sweat. Green indicates a low amount of sweat. Blue indicates almost no sweat.

Figure 5

Changes in the sweat rate before and after Toloese bed usage. (a,b) represent the changes in the exhalation rate of the upper and lower body of males, respectively. (c,d) depict the changes in the sweat rate of the upper and lower body of females in each week. Values were expressed as mean ± standard deviation. One-way ANOVA was used to compare the pre-exposure measurements at week 0 with the post-exposure measurements for each subsequent week. ** p < 0.01; *** p < 0.001 for 0 week vs. each week. # p < 0.05 for 1 week vs. 3 weeks.