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. 2024 Jun 20;16(3):663-672.
doi: 10.3390/neurolint16030050.

Anesthesia for Endovascular Therapy for Stroke

Affiliations

Anesthesia for Endovascular Therapy for Stroke

Arianna Gaspari et al. Neurol Int. .

Abstract

Background: In patients with acute ischemic stroke, the standard of care is to perform intra-arterial endovascular thrombectomy in addition to intravenous thrombolysis. In this study, we investigated the different anesthetic techniques chosen for this procedure and clinical outcomes.

Methods: Patients undergoing endovascular procedures were divided into three groups. The first group consisted of patients who received general anesthesia, the second group underwent the procedure under conscious sedation and local anesthesia at the catheter insertion site, and lastly the third group included patients who received only local anesthesia at the catheter insertion site, without sedation.

Results: During the endovascular procedure, we did not notice significant differences in vital parameters, in particular the mean blood pressure (MAP) between patients treated with different types of anesthesia. Also, the duration of the revascularization did not show significant differences between the three groups. The main point is the absence of differences in terms of functional and clinical outcomes, using various scores as reference, such as the National Institutes of Health Stroke Scale (NIHSS) score at 7 days, NIHSS and Modified Rankin Scale (MRS) at time of discharge, and MRS after 3 months. These scores did not show significant differences in groups treated with different types of anesthesia.

Conclusions: The rate of success of the revascularization procedure is almost overlapping between patients treated with conscious sedation and general anesthesia. In addition, we did not notice significant differences between groups in terms of functional and clinical outcomes. Considering the possible usefulness of applying conscious sedation, at OCSAE of Baggiovara, an internal protocol for conscious sedation was introduced to standardize the treatment in patients undergoing endovascular procedures.

Keywords: conscious sedation; endovascular therapy; stroke.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure A1
Figure A1
Protocol suggested by l’AOU OCSAE di Baggiovara (MO) equipe for conscious sedation.

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References

    1. Soto A., Guillén-Grima F., Morales G., Muñoz S., Aguinaga-Ontoso I., Fuentes-Aspe R. Prevalence and incidence of ictus in Europe: Systematic review and meta-analysis. An. Sist. Sanit. Navar. 2022;45:e0979. doi: 10.23938/assn.0979. - DOI - PMC - PubMed
    1. Turc G., Bhogal P., Fischer U., Khatri P., Lobotesis K., Mazighi M., Schellinger P.D., Toni D., de Vries J., White P., et al. European Stroke Organisation (ESO)-European Society for Minimally Invasive Neurological Therapy (ESMINT) guidelines on mechanical thrombectomy in acute ischemic stroke. J. Neurointerv. Surg. 2019;11:535–538. doi: 10.1136/neurintsurg-2018-014568. - DOI - PubMed
    1. Wahlgren N., Moreira T., Michel P., Steiner T., Jansen O., Cognard C., Mattle H.P., van Zwam W., Holmin S., Tatlisumak T., et al. Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Int. J. Stroke. 2016;11:134–147. doi: 10.1177/1747493015609778. - DOI - PubMed
    1. Schönenberger S., Bösel J. Reply from Schönenberger et al. to the letter from Kofke and Sharma regarding “Sedation vs. Intubation for Endovascular Stroke TreAtment (SIESTA)—A randomized monocentric trial”. Int. J. Stroke. 2016;11:NP73. doi: 10.1177/1747493016641117. - DOI - PubMed
    1. Schönenberger S., Möhlenbruch M., Pfaff J., Mundiyanapurath S., Kieser M., Bendszus M., Hacke W., Bösel J. Sedation vs. Intubation for Endovascular Stroke TreAtment (SIESTA)—A randomized monocentric trial. Int. J. Stroke. 2015;10:969–978. doi: 10.1111/ijs.12488. - DOI - PubMed

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