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Case Reports
. 2024 Dec;13(1):2373305.
doi: 10.1080/22221751.2024.2373305. Epub 2024 Jul 16.

Early neurosyphilis with serofast state

Souheil Zayet  1 , Samantha Poloni  1 , Vincent Gendrin  1 , Johan Chanal  2   3 , Nicolas Dupin  2   3 , Timothée Klopfenstein  1
Affiliations
Case Reports

Early neurosyphilis with serofast state

Souheil Zayet et al. Emerg Microbes Infect. 2024 Dec.

Abstract

We report a rare case of confirmed early neurosyphilis with serofast state in HIV-negative patient, with uncontrolled type 2 diabetes mellitus. Syphilitic meningitis was diagnosed initially on serology and cerebrospinal fluid (CSF) analysis. The patient had persistently raised non-treponemal titres on serum with negative CSF venereal disease research laboratory result, following treatment during 3 years of follow-up.

Keywords: Neurosyphilis; cerebrospinal fluid; meningitis; nontreponemal antibodies; serofast.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

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