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. 1985 Apr;33(4):266-74.

Elastin covalent structure as determined by solid phase amino acid sequencing

L B Sandberg, J G Leslie, C T Leach, V L Alvarez, A R Torres, D W Smith
  • PMID: 3892457

Elastin covalent structure as determined by solid phase amino acid sequencing

L B Sandberg et al. Pathol Biol (Paris). 1985 Apr.

Abstract

The amino acid sequences of 16 large tryptic fragments of aortic tropoelastin have been determined establishing the presence of several repeating structures: GVP, GGVP, PGVGV, PGVGVA, and AGVPGFGVG. The methodologies for achieving these results by solid phase sequencing are reviewed and also the possible biologic significance of the unusual primary structures of elastin are discussed.

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