Retraction Note: Microbiome analyses of blood and tissues suggest cancer diagnostic approach

Gregory D Poore^#¹, Evguenia Kopylova^#^{2

3}, Qiyun Zhu², Carolina Carpenter⁴, Serena Fraraccio⁴, Stephen Wandro⁴, Tomasz Kosciolek^{2

5}, Stefan Janssen^{2

6}, Jessica Metcalf⁷, Se Jin Song^{2

4}, Jad Kanbar⁸, Sandrine Miller-Montgomery^{1

4}, Robert Heaton⁹, Rana Mckay¹⁰, Sandip Pravin Patel^{4

10}, Austin D Swafford⁴, Rob Knight^{11

12

13

14}

Affiliations

¹ Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
² Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
³ Clarity Genomics, Beerse, Belgium.
⁴ Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
⁵ Malopolska Centre of Biotechnology, Jagiellonian University in Krakow, Krakow, Poland.
⁶ Algorithmic Bioinformatics, Department of Biology and Chemistry, Justus Liebig University Gießen, Gießen, Germany.
⁷ Department of Animal Sciences, Colorado State University, Fort Collins, CO, USA.
⁸ Department of Medicine, University of California San Diego, La Jolla, CA, USA.
⁹ Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
¹⁰ Moores Cancer Center, University of California San Diego Health, La Jolla, CA, USA.
¹¹ Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.
¹² Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.
¹³ Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.
¹⁴ Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.

^# Contributed equally.

Gregory D Poore et al. Nature. 2024 Jul.

. 2024 Jul;631(8021):694.

doi: 10.1038/s41586-024-07656-x.

¹ Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
² Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
³ Clarity Genomics, Beerse, Belgium.
⁴ Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
⁵ Malopolska Centre of Biotechnology, Jagiellonian University in Krakow, Krakow, Poland.
⁶ Algorithmic Bioinformatics, Department of Biology and Chemistry, Justus Liebig University Gießen, Gießen, Germany.
⁷ Department of Animal Sciences, Colorado State University, Fort Collins, CO, USA.
⁸ Department of Medicine, University of California San Diego, La Jolla, CA, USA.
⁹ Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
¹⁰ Moores Cancer Center, University of California San Diego Health, La Jolla, CA, USA.
¹¹ Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.
¹² Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.
¹³ Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.
¹⁴ Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.

^# Contributed equally.

No abstract available

Retraction of

Microbiome analyses of blood and tissues suggest cancer diagnostic approach.
Poore GD, Kopylova E, Zhu Q, Carpenter C, Fraraccio S, Wandro S, Kosciolek T, Janssen S, Metcalf J, Song SJ, Kanbar J, Miller-Montgomery S, Heaton R, Mckay R, Patel SP, Swafford AD, Knight R. Poore GD, et al. Nature. 2020 Mar;579(7800):567-574. doi: 10.1038/s41586-020-2095-1. Epub 2020 Mar 11. Nature. 2020. Retraction in: Nature. 2024 Jul;631(8021):694. doi: 10.1038/s41586-024-07656-x. PMID: 32214244 Free PMC article. Retracted.

1. Gihawi, A. et al. Major data analysis errors invalidate cancer microbiome findings. mBio 14, e01607–23 (2023). - DOI - PubMed - PMC
1. Sepich-Poore, G. D. et al. Robustness of cancer microbiome signals over a broad range of methodological variation. Oncogene 43, 1127–1148 (2024). - DOI - PubMed - PMC