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Review
. 2024 Jun 9;25(12):6388.
doi: 10.3390/ijms25126388.

Cardiovascular Effects of Herbal Products and Their Interaction with Antihypertensive Drugs-Comprehensive Review

Kinga-Ilona Nyulas  1 , Zsuzsánna Simon-Szabó  2 , Sándor Pál  3 , Márta-Andrea Fodor  4 , Lóránd Dénes  5 , Margit Judit Cseh  6 , Enikő Barabás-Hajdu  7 , Bernadett Csipor  1 , Juliánna Szakács  8 , Zoltán Preg  9 , Márta Germán-Salló  10 , Enikő Nemes-Nagy  11
Affiliations
Review

Cardiovascular Effects of Herbal Products and Their Interaction with Antihypertensive Drugs-Comprehensive Review

Kinga-Ilona Nyulas et al. Int J Mol Sci. .

Abstract

Hypertension is a highly prevalent population-level disease that represents an important risk factor for several cardiovascular complications and occupies a leading position in mortality statistics. Antihypertensive therapy includes a wide variety of drugs. Additionally, the potential antihypertensive and cardioprotective effects of several phytotherapy products have been evaluated, as these could also be a valuable therapeutic option for the prevention, improvement or treatment of hypertension and its complications. The present review includes an evaluation of the cardioprotective and antihypertensive effects of garlic, Aloe vera, green tea, Ginkgo biloba, berberine, ginseng, Nigella sativa, Apium graveolens, thyme, cinnamon and ginger, and their possible interactions with antihypertensive drugs. A literature search was undertaken via the PubMed, Google Scholar, Embase and Cochrane databases. Research articles, systematic reviews and meta-analyses published between 2010 and 2023, in the English, Hungarian, and Romanian languages were selected.

Keywords: antihypertensive drugs; herbal products; herb–drug interaction; hypertension; phytotherapy.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Cardiovascular effects of the medicinal plants.
Figure 2
Figure 2
Drug–herb interactions.
See this image and copyright information in PMC

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