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. 2023 Dec 26;23(1):967-976.
doi: 10.1007/s40200-023-01373-4. eCollection 2024 Jun.

The association between frailty and body composition among the elderly: Birjand Longitudinal Aging Study (BLAS)

Maysa Eslami  1 , Hossein Fakhrzadeh  2 , Farzad Pourghazi  1 , Mitra Moodi  3   4 , Zohreh Sajadi Hezaveh  5 , Seyed Masoud Arzaghi  2 , Huriye Khodabakhshi  3 , Masoumeh Khorashadizadeh  3 , Hanieh-Sadat Ejtahed  6 , Farshad Sharifi  2
Affiliations

The association between frailty and body composition among the elderly: Birjand Longitudinal Aging Study (BLAS)

Maysa Eslami et al. J Diabetes Metab Disord. .

Abstract

Background: This study aims to assess the possible relationship between frailty and anthropometric indices in older adults using data from the first phase of the Birjand Longitudinal Aging Study (BLAS).

Methods: In this cross-sectional study, we assessed the association between frailty (Frailty index (FI) and Fried frailty phenotype) and body composition indices in 1364 participants aged ≥ 60 years (September 2018 to April 2019). Analysis was conducted using one-way ANOVA and ordinal logistic regression.

Results: Participants were categorized as frail (n = 164), non-frail (n = 415), and pre-frail (n = 785) based on FI. A significant positive association was observed between the frailty and body mass index (BMI) (OR: 1.04, 95% CI:1.01- 1.07), waist circumference (WC) (OR: 1.02, 95% CI: 1.01- 1.03), waist-to-hip ratio (WHR) (OR: 2.36, 95% CI 1.05- 5.27) and waist-to-height ratio (WHtR) (OR: 1.27, 95%CI: 1.09- 1.47). Body shape index, body roundness index, and body adiposity index showed no significant association with frailty. Moreover, a BMI greater than 29 kg/m2 increased the odds of frailty and prefrailty by 79% (OR = 1.79, 95%CI = 1.30- 2.46, P < 0.001).

Conclusion: Results of this study showed that the risk of frailty increases as BMI and abdominal obesity indices increase. Therefore, BMI and abdominal obesity indices (WC, WHR, and WHtR) could serve as suitable tools for evaluating frailty in the elderly. However, additional studies are needed to evaluate the utility of the newly developed anthropometric indices in older adults.

Keywords: Aging; Body composition; Elderly; Frailty syndrome; Obesity.

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Conflict of interest statement

Competing InterestsThe authors declared that they have no conflict of interest.

References

    1. Organization WH. Are you ready? What you need to know about ageing. World health day. 2012.
    1. United Nations, Department of Economic and Social Affairs, Population Division. World Population Ageing. 2017.
    1. O’Caoimh R, Sezgin D, O’Donovan MR, Molloy DW, Clegg A, Rockwood K, et al. Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies. Age Ageing. 2021;50(1):96–104. - PubMed
    1. Jafaripour S, Omidvar N, Eini-Zinab H, Rezaei M, Rezazadeh A. Prevalence of Frailty and Its Relationships with Malnutrition in Elderly Living in Tehran City, 2021. Iran J Nutrition Sci Food Technol. 2023;17(4):19–29.
    1. Delbari A, Zanjari N, Momtaz YA, Rahim F, Saeidimehr S. Prevalence of frailty and associated socio-demographic factors among community-dwelling older people in southwestern Iran: a cross-sectional study. J Diabetes Metab Disord. 2021;20(1):601–610. - PMC - PubMed

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