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Case Reports
. 2024 Mar 25;23(1):1415-1418.
doi: 10.1007/s40200-024-01410-w. eCollection 2024 Jun.

A severe pediatric life-threatening metabolic ketoacidosis

Charlotte Roulland  1   2 , Catline Le Pallec  3 , Caroline Faucon  3 , Camille O Andre  3 , Alina Arion  3 , Isabelle Goyer  4 , David Brossier  1   5   6   7
Affiliations
Case Reports

A severe pediatric life-threatening metabolic ketoacidosis

Charlotte Roulland et al. J Diabetes Metab Disord. .

Abstract

This case report presents a 9-year-old child without underlying pathology, with a severe life-threatening non-diabetic metabolic ketoacidosis occurring less than 48 h after the onset of fasting and vomiting. The patient was admitted to the pediatric intensive care unit. He received volume expansion and maintenance fluid therapy which allowed a favorable evolution. Because of the unusual rapid onset of intense ketonemia and acidosis, a hereditary metabolic disease was investigated. The association between short fasting period and severe metabolic ketoacidosis has never been described in children outside of the neonatal period. This clinical case emphasizes urgent recognition, rigorous diagnostic and appropriate management in clinical practice.

Keywords: Intensive care; Ketoacidosis; Non-diabetic; Pediatric.

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Conflict of interest statement

Conflict of interestAll authors have no conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1
pH, Plasma glucose and ketone bodies concentration according to carbohydrate intake
See this image and copyright information in PMC

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