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. 2025 Mar;112(3):270-276.
doi: 10.1016/j.bulcan.2024.04.015. Epub 2024 Jun 26.

[Prophylactic surgery for hepatic and biliary tumors]

[Article in French]
Affiliations

[Prophylactic surgery for hepatic and biliary tumors]

[Article in French]
Alexandra Nassar et al. Bull Cancer. 2025 Mar.

Abstract

Benign tumors of the liver and biliary tract are rare entities, and some of them require surgical management to prevent their malignant transformation. Tumors from the biliary tract with malignant potential are treated either by hepatic resection, for mucinous cystic neoplasm and ciliated hepatic foregut cysts, or by biliary resections, for biliary papillary neoplasm and type I and IV choledochal cysts. The pathologies requiring prophylactic cholecystectomy are polyps larger than 10 mm, porcelain gallbladder and pancreaticobiliary maljunction. Finally, hepatocellular adenoma over 5cm, occurring in male patients, or exon 3 mutated beta-catenin, should lead to prophylactic resection by hepatic segmentectomy. This article describes these different pathologies and their management.

Keywords: Benign tumors; Biliary tract tumors; Chirurgie prophylactique; Liver tumors; Prophylactic surgery; Tumeur bénigne du foie; Tumeurs biliaires bénignes.

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