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Case Reports
. 2024 May 27;16(5):e61192.
doi: 10.7759/cureus.61192. eCollection 2024 May.

Clinical, Dermoscopic and Histopathological Features of Non-melanoma Skin Cancers in People With Skin of Colour: A Series of Five Cases

Guntamukkala Geeta Sai  1 , Sheba Mariam Jacob  1 , Sai Kavya D  1 , Anannya S  1 , Afthab Jameela Wahab  1 , Vimal Chander R  2
Affiliations
Case Reports

Clinical, Dermoscopic and Histopathological Features of Non-melanoma Skin Cancers in People With Skin of Colour: A Series of Five Cases

Guntamukkala Geeta Sai et al. Cureus. .

Abstract

Non-melanoma skin cancers (NMSC) such as basal cell carcinoma (BCC) as well as squamous cell carcinoma (SCC) are the two most common skin malignancies globally. They are observed more frequently among Caucasians than Asians, and their incidence is inversely proportional to the pigmentation levels. Even though the occurrence of skin cancers in India is lower, the absolute quantity of cases may be considerable due to the vast population. Here, we report five cases of NMSC in people having skin of colour.

Keywords: basal cell carcinoma; case series; dermatology; nonmelanoma skin cancer; squamous cell carcinoma.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Well-defined verrucous exophytic plaque with erosions and surrounding hyperpigmented margin over the right palm and middle finger
Figure 2
Figure 2. Dermoscopy showing keratin mass (orange arrow), surface scaling (black arrow), white pink structureless area (red arrow).
Figure 3
Figure 3. Tissue section stained with hematoxylin and eosin (10X magnification) showing hyperkeratosis, acanthosis, vacuolated keratinocytes, full thickness loss of polarity (black star).
Figure 4
Figure 4. Post operative image.
Figure 5
Figure 5. Well defined hyperpigmented plaque with central ulceration and rolled margins over the forehead.
Figure 6
Figure 6. Dermoscopy showing arborizing blood vessels (black arrow), blue grey areas (yellow arrow).
Figure 7
Figure 7. Tissue section stained with hematoxylin and eosin (10X magnification) showing basaloid cell nests with peripheral palisading pattern (black star).
Figure 8
Figure 8. Post operative image.
Figure 9
Figure 9. Well defined hyperpigmented plaque with crusting over the left shoulder and back.
Figure 10
Figure 10. Dermoscopy showing keratin mass (blue arrow), surface scaling (red arrow), erosions (yellow arrow), blue grey structureless area (white star).
Figure 11
Figure 11. Tissue section stained with hematoxylin and eosin (10X magnification) illustrating malignant neoplasm composed of basaloid cell nests (black star).
Figure 12
Figure 12. Tissue section stained with hematoxylin and eosin (10X magnification) illustrating focal keratin pearl.
Figure 13
Figure 13. Post operative image showing graft rejection.
Figure 14
Figure 14. Single erythematous verrucous plaque over the left gluteal region.
Figure 15
Figure 15. Dermoscopy showing surface keratin (blue arrow), white structureless area (green arrow), multiple branched blood vessels (black arrow).
Figure 16
Figure 16. Tissue section stained with hematoxylin and eosin (10x magnification) illustrating anastomosing bundles and nests of polygonal cells with pleomorphic hyperchromatic nuclei with a pushing border.
Figure 17
Figure 17. Post operative image
Figure 18
Figure 18. Well defined exophytic growth with ulceration, bloody discharge from few areas, crusting over posterolateral aspect of right foot
Figure 19
Figure 19. Dermoscopy showing dotted and coma shaped vessels (black arrow), keratin mass (blue arrow), erosions (green arrow).
Figure 20
Figure 20. Tissue section stained with hematoxylin and eosin (100X magnification) showing dermis with irregular nests and sheets of malignant squamous cells.
Figure 21
Figure 21. Post operative image
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