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Case Reports
. 2024 Jun 3:54:101429.
doi: 10.1016/j.gore.2024.101429. eCollection 2024 Aug.

Endometrial large cell neuroendocrine carcinoma: A case report and literature review

Feng Yang  1 , Shoujun Liang  1 , Chuanzhong Liu  1 , Yeping Wei  1 , Liying Zhang  1
Affiliations
Case Reports

Endometrial large cell neuroendocrine carcinoma: A case report and literature review

Feng Yang et al. Gynecol Oncol Rep. .

Abstract

Endometrial large cell neuroendocrine carcinoma (LCNEC) is a highly malignant tumor that presents with neuroendocrine function. It is difficult to diagnose at an early stage. Moreover, the diagnosis depends on the pathological and immunohistochemical findings. It is also prone to distant metastasis, but is difficult to treat and shows poor prognosis. Presently, there exists no unified treatment plan, and the prognosis of this disease is also poor. We reported here an analysis and literature review of a case of endometrial LCNEC to facilitate the comprehension of this disease and provide help toward clinical diagnosis and treatment.

Keywords: Endometrium; Immunohistochemistry; Large cell neuroendocrine carcinoma.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Pelvic ultrasound (A and B) and CT (C and D) showing a soft tissue mass protruding from the uterine cavity to the cervical area.
Fig. 2
Fig. 2
Intrauterine masses in the removd uterus.
Fig. 3
Fig. 3
CT (A and B) showing multiorgan metastases after treatment.
See this image and copyright information in PMC

References

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