Primary Hyperparathyroidism: Part Two: Surgical Management

Abstract

Primary hyperparathyroidism (PHPT) is caused by the overproduction of parathyroid hormone by 1 or more parathyroid glands resulting in hypercalcemia and its downstream clinical consequences. The definitive management of PHPT is surgery. Approaches to successful surgery include bilateral exploration or focused parathyroidectomy with intraoperative parathyroid hormone monitoring, which in experienced hands are both associated with a low risk of complications.

Keywords: Benign adenoma; Bilateral neck exploration; Enhanced recovery after surgery; Focused parathyroidectomy; Hypercalcemia; Management of primary hyperparathyroidism; Multiglandular disease; Parathyroid surgery.