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. 2024 May 22;27(6):110074.
doi: 10.1016/j.isci.2024.110074. eCollection 2024 Jun 21.

Different trends of gastric cancer in China, Japan, Republic of Korea and United States of America

Fangrui Zhao  1 , Dashuai Yang  2 , Yanfang Lan  1 , Xiangpan Li  1
Affiliations

Different trends of gastric cancer in China, Japan, Republic of Korea and United States of America

Fangrui Zhao et al. iScience. .

Abstract

Gastric cancer exerts a significant healthcare burden worldwide and is highly geographically heterogeneous. This study investigates the burden of gastric cancer in China from 1990 to 2019 and compares it with Japan, South Korea, and the United States. The results indicated a declining trend in ASIR and ASDR in four countries. However, the incidence and death rates in China remain disproportionately high. Significant gender disparities exist in the incidence and death rates, with males experiencing significantly higher rates than females. Incidence and death rates were found to increase with age in all studied countries. In China, a transient upward trend was observed in the period effect, whereas the cohort effect has been declining. In contrast, the remaining countries showed decreasing patterns in both period and cohort effects. The burden of disease remains high in China, therefore, broaden the scope of gastroscopy screening and concentrate on high-risk groups is vital.

Keywords: Health sciences; Oncology; Public health.

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Conflict of interest statement

The authors declare no competing interests.

Figures

None
Graphical abstract
Figure 1
Figure 1
Age-standardized disease burden of gastric cancer among China, Japan, Republic of Korea, and United States of America from 1990 to 2019 (A) ASIR of gastric cancer among four countries from 1990 to 2019. (B) ASDR of gastric cancer among four countries from 1990-201. ASIR, age-standardized incidence rate; ASDR, age-standardized death rate.
Figure 2
Figure 2
Trends in disease burden of gastric cancer across different countries in male patients from 1990 to 2019 (A) Trends in the incidence rate of gastric cancer in male patients from 1990 to 2019. (B) Trends in the mortality rate of gastric cancer in male patients from 1990 to 2019.
Figure 3
Figure 3
Trends in the disease burden of gastric cancer across different countries in female patients from 1990 to 2019 (A) Trends in the incidence rate of gastric cancer in female patients from 1990 to 2019. (B) Trends in the mortality rate of gastric cancer in female patients from 1990 to 2019.
Figure 4
Figure 4
Age-Period-Cohort Model analysis of gastric cancer incidence among China, Japan, Republic of Korea, and United States of America
Figure 5
Figure 5
Age-Period-Cohort Model analysis of gastric cancer mortality among China, Japan, Republic of Korea, and United States of America
See this image and copyright information in PMC

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