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. 2024 Jun;10(2):33.
doi: 10.3390/beverages10020033. Epub 2024 May 1.

Common Beverage Consumption and Benign Gynecological Conditions

Rachel Michel  1 , Dana Hazimeh  2 , Eslam E Saad  2 , Sydney L Olson  2 , Kelsey Musselman  2 , Eman Elgindy  3 , Mostafa A Borahay  2
Affiliations

Common Beverage Consumption and Benign Gynecological Conditions

Rachel Michel et al. Beverages (Basel). 2024 Jun.

Abstract

The purpose of this article is to review the effects of four commonly consumed beverage types-sugar-sweetened beverages (SSBs), caffeinated beverages, green tea, and alcohol-on five common benign gynecological conditions: uterine fibroids, endometriosis, polycystic ovary syndrome (PCOS), anovulatory infertility, and primary dysmenorrhea (PD). Here we outline a plethora of research, highlighting studies that demonstrate possible associations between beverage intake and increased risk of certain gynecological conditions-such as SSBs and dysmenorrhea-as well as studies that demonstrate a possible protective effect of beverage against risk of gynecological condition-such as green tea and uterine fibroids. This review aims to help inform the diet choices of those with the aforementioned conditions and give those with uteruses autonomy over their lifestyle decisions.

Keywords: anovulatory infertility; endometriosis; polycystic ovary syndrome (PCOS); primary dysmenorrhea (PD); uterine fibroids (UF).

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Conflict of interest statement

Conflicts of Interest: The authors declare no conflicts of interest.

Figures

Figure 1.
Figure 1.
Effect of sugar-sweetened beverage (SSB) consumption on pro-tumorigenic pathways contributing to fibroid development.
Figure 2.
Figure 2.
Effect of Epigallocatechin gallate (EGCG) on pro-angiogenic cellular signaling pathways, which acts by downregulating vascular epithelial growth factors (VEGF).
Figure 3.
Figure 3.
Mechanism of polycystic ovary syndrome (PCOS) onset.
Figure 4.
Figure 4.
Normal hypothalamic-pituitary-ovarian (HPO) axis mechanism involving interaction of hypothalamic gonadotropin-releasing hormone (GnRH), follicle stimulating hormone (FSH) and luteinizing hormone (LH).
Figure 5.
Figure 5.
Mechanism of primary dysmenorrhea.
See this image and copyright information in PMC

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