Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jan;50(1):24-37.
doi: 10.1007/s00261-024-04472-9. Epub 2024 Jul 1.

Peribiliary cysts: uncommon mimickers of hepatic and biliary cystic lesions

Ana Cláudia Vincenzi Raduan Uski  1 , Maria Helena Naves Inácio Pedroso  2 , Carolina Pereira Abud  2 , Marina Martini Costa  2 , Marília Paes Fortes Diniz Ferreira  2
Affiliations

Peribiliary cysts: uncommon mimickers of hepatic and biliary cystic lesions

Ana Cláudia Vincenzi Raduan Uski et al. Abdom Radiol (NY). 2025 Jan.

Abstract

Peribiliary cysts (PC) are dilatations of the extramural peribiliary glands, with a very characteristic imaging pattern in the contexts of hepatobiliary diseases, idiopathic portal hypertension, adult-type polycystic disease of the liver and kidneys, solitary nonparasitic cysts, and systemic infections. The clinical relevance of PC is related to the fact that their presence may indicate underlying pathologies (such as those mentioned above) and may be considered as a potential marker of liver disease progression. Although imaging findings are quite characteristic, recognizing their main differential diagnoses, including malignancies, can be challenging but are essential to avoiding diagnostic errors.

Keywords: Cysts; Hepatobiliary; Peribiliary.

PubMed Disclaimer

Conflict of interest statement

Declarations. Competing interest: The authors did not receive support from any organization for the submitted work. The authors have no competing interests to declare that are relevant to the content of this article.

References

    1. Nakanuma, Y. (2001) Peribiliary cysts: a hitherto poorly recognized disease. Journal of Gastroenterology and Hepatology 16: 1081-1083. https://doi.org/10.1046/j.1440-1746.2001.02604.x . - DOI - PubMed
    1. Bazerbachi F, Haffar S, Sugihara T (2018) Peribiliary cysts: a systematic review and proposal of a classification framework. BMJ Open Gastroenterology 5: e204. - DOI
    1. Kai K, et al (2008) An autopsy case of obstructive jaundice due to hepatic multiple peribiliary cysts accompanying hepatolithiasis. Hepatology Research 38.2: 211-216. - DOI - PubMed
    1. de Jong IEM, et al (2018) Repopulating the biliary tree from the peribiliary glands. Biochimica et Biophysica Acta (BBA)—Molecular Basis of Disease 1864.4: 1524-1531.
    1. Itai Y, et al (1994) Hepatic peribiliary cysts: multiple tiny cysts within the larger portal tract, hepatic hilum, or both. Radiology 191.1: 107-110. - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources