Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Jul 1;12(7):e8920.
doi: 10.1002/ccr3.8920. eCollection 2024 Jul.

Management of extensive portal vein thrombosis via thrombolysis and thrombectomy without underlying liver disease: A case report

Mohammadshah Isam Gul  1 , Waseem Umer  1 , Ahmed Daniyal Nawaz  2 , Mohammad J H Elhissi  3 , Muhammad Zahid  1   2   4
Affiliations
Case Reports

Management of extensive portal vein thrombosis via thrombolysis and thrombectomy without underlying liver disease: A case report

Mohammadshah Isam Gul et al. Clin Case Rep. .

Abstract

Portal vein thrombosis (PVT) is a rare condition, particularly in non-cirrhotic patients. Anticoagulation remains the mainstay of the treatment. Extensive PVT can lead to variceal bleeding, ascites, bowel ischemia, and hypersplenism. The role of thrombolysis and thrombectomy in these patients remains unclear. However, there is evidence that local thrombolysis and thrombectomy should be considered in those who remain symptomatic on anticoagulation and are at risk of complications with acute PVT.

Keywords: anticoagulation; case report; liver cirrhosis; portal vein thrombosis; thrombectomy; thrombolysis.

PubMed Disclaimer

Conflict of interest statement

In compliance with the ICMJE uniform disclosure form, all authors declare no actual or potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Pre‐thrombectomy portal venogram; the tip of the catheter (arrow) is in the SMV with the retrograde flow of contrast with collaterals.
FIGURE 2
FIGURE 2
A post‐thrombectomy portal venogram; the tip of the catheter is in the SMV with the antegrade flow of contrast with the disappearance of collaterals. A few remnant thrombi (Arrows) persist in the SMV.
See this image and copyright information in PMC

References

    1. Kalra A, Yetiskul E, Wehrle CJ, Tuma F. Physiology, liver. StatPearls. StatPearls Publishing LLC; 2024. - PubMed
    1. Ogren M, Bergqvist D, Björck M, Acosta S, Eriksson H, Sternby NH. Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies. World J Gastroenterol. 2006;12(13):2115‐2119. - PMC - PubMed
    1. Rajani R, Björnsson E, Bergquist A, et al. The epidemiology and clinical features of portal vein thrombosis: a multicentre study. Aliment Pharmacol Ther. 2010;32(9):1154‐1162. - PubMed
    1. Francoz C, Valla D, Durand F. Portal vein thrombosis, cirrhosis, and liver transplantation. J Hepatol. 2012;57(1):203‐212. - PubMed
    1. Francoz C, Belghiti J, Vilgrain V, et al. Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation. Gut. 2005;54(5):691‐697. - PMC - PubMed

Publication types

LinkOut - more resources