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. 2024 Jul 2;22(1):51.
doi: 10.1186/s12955-024-02266-7.

The EQ-5D-5L valuation study for Trinidad and Tobago

Henry Bailey  1   2 , Marcel F Jonker  3   4   5 , Eleanor Pullenayegum  6 , Fanni Rencz  7 , Bram Roudijk  8   9
Affiliations

The EQ-5D-5L valuation study for Trinidad and Tobago

Henry Bailey et al. Health Qual Life Outcomes. .

Abstract

Purpose: The 2016 EQ-5D-3L value set for Trinidad and Tobago (T&T) allows for the calculation of EQ-5D-5L values via the crosswalk algorithm. The 2016 value set was based on methods predating the EQ-VT protocol, now considered the gold standard for developing EQ-5D value sets. Furthermore, direct elicitation of EQ-5D-5L is preferred over crosswalked values. This study aimed to produce an EQ-5D-5L value set for T&T.

Methods: A representative sample (age, sex, geography) of adults each completed 10 composite Time Trade-Off (cTTO) tasks and 12 Discrete Choice Experiment (DCE) tasks in face-to-face interviews. The cTTO data were analyzed using a Tobit model that corrects for heteroskedasticity. DCE data were analyzed using a mixed logit model. The cTTO and DCE data were combined in hybrid models.

Results: One thousand and seventy-nine adults completed the valuation interviews. Among the modelling approaches that were explored, the hybrid heteroskedastic Tobit model produced all internally consistent, statistically significant coefficients, and performed best in terms of out-of-sample predictivity for single states. Compared to the existing EQ-5D-5L crosswalk set, the new value set had a higher number of negative values (236 or 7.6% versus 21 or 0.7%). The mean absolute difference was 0.157 and the correlation coefficient between the two sets was 0.879.

Conclusion: This study provides a value set for the EQ-5D-5L for T&T using the EQ-VT protocol. We recommend this value set for QALY computations relating to T&T.

Keywords: EQ-5D-5L; EQ-VT; QALY; Trinidad and Tobago.

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Conflict of interest statement

Eleanor Pullenayegum and Fanni Rencz are on the Editorial Board of Health and Quality of Life Outcomes. All of the authors are members of the EuroQol Research Foundation. Bram Roudijk is employed by the EuroQol Research Foundation.

Figures

Fig. 1
Fig. 1
Responses to the cTTO task
Fig. 2
Fig. 2
Bland–Altman plot for the crosswalk versus the EQ-VT value set On the vertical axis, the difference between the crosswalk and EQ-VT value sets is shown for all 3125 health states. On the horizontal axis, the average value of the crosswalk and EQ-VT value set is shown for each health state
See this image and copyright information in PMC

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