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Review
. 2024 Jun 18:12:1396408.
doi: 10.3389/fped.2024.1396408. eCollection 2024.

Synthesis of current pediatric urinary microbiome research

Layla M Jeries  1 , Tatyana A Sysoeva  1 , Lisa Karstens  2   3 , Maryellen S Kelly  4   5
Affiliations
Review

Synthesis of current pediatric urinary microbiome research

Layla M Jeries et al. Front Pediatr. .

Abstract

The human urinary bladder hosts a complex microbial community of low biomass referred to as the urobiome. While the composition of the urobiome has been investigated in adults for over a decade now, only a few studies have considered the presence and composition of the urobiome in children. It is critical to explore how the urobiome develops throughout the life span and how it changes in the presence of various health conditions. Therefore, we set to review the available data on pediatric urobiome composition and its development with age and disease. In addition, we focused on identifying and reporting specific gaps in our knowledge of the pediatric urobiome that we hope will be addressed by future studies in this swiftly developing field with fast-improving methods and consensus.

Keywords: pediatric bladder microbiome; pediatric urobiome; urinary microbiome; urinary mycobiome; urinary virome; urobiome.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Summary of variables affecting observed urobiome composition.
See this image and copyright information in PMC

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