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Editorial
. 2024 Jul;30(7):e14777.
doi: 10.1111/cns.14777.

Building evidence on safety of endovascular thrombectomy for patients under anticoagulation with vitamin K antagonists

Li Gao  1 , Xiaowei Sun  2 , Peiying Li  2   3
Affiliations
Editorial

Building evidence on safety of endovascular thrombectomy for patients under anticoagulation with vitamin K antagonists

Li Gao et al. CNS Neurosci Ther. 2024 Jul.

Abstract

A recent study by Brian Mac Grory and colleagues investigated the safety of endovascular thrombectomy (EVT) among patients under vitamin K antagonists (VKAs) use within 7 days prior to hospital admission. Through this retrospective, observational cohort study, they found prior VKA use did not increase the risk of symptomatic intracranial hemorrhage (sICH) overall. However, recent VKA use with a presenting international normalized ratio (INR) > 1.7 was associated with a significantly increased risk of sICH. Future large-scale randomized controlled trials should be conducted to further clarify the effects and feasibility of EVT therapy in ischemic stroke patients under anticoagulation.

Keywords: anticoagulation; endovascular thrombectomy; ischemic stroke; symptomatic intracranial hemorrhage; vitamin K antagonists.

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Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the authorship, and/or publication of this article. Peiying Li is an Editorial Board member of CNS Neuroscience and Therapeutics and a co‐author of this article. To minimize bias, they were excluded from all editorial decision‐making related to the acceptance of this article for publication.

Comment on

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