A nose for tau

Soraya Meftah^{1

2}, Claire S Durrant^{1

2}, Tara L Spires-Jones^{1

2}

Affiliations

¹ UK Dementia Research Institute at University of Edinburgh, Edinburgh EH8 9JZ, UK.
² Centre for Discovery Brain Sciences, School of Biomedical Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh EH8 9JZ, UK.

Review

Soraya Meftah et al. Sci Transl Med. 2024.

. 2024 Jul 3;16(754):eadq6489.

doi: 10.1126/scitranslmed.adq6489. Epub 2024 Jul 3.

Soraya Meftah^{1

2}, Claire S Durrant^{1

2}, Tara L Spires-Jones^{1

2}

¹ UK Dementia Research Institute at University of Edinburgh, Edinburgh EH8 9JZ, UK.
² Centre for Discovery Brain Sciences, School of Biomedical Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh EH8 9JZ, UK.

Abstract

Nasal delivery of an oligomeric tau antibody loaded into micelles reduces pathology and ameliorates cognition in a mouse model of tauopathy.