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Review
. 1985 Jun;5(3):179-90.
doi: 10.1016/0166-3542(85)90050-6.

The potential use of liposome-mediated antiviral therapy

Review

The potential use of liposome-mediated antiviral therapy

W C Koff et al. Antiviral Res. 1985 Jun.

Abstract

The natural targeting of liposomes to cells of the reticuloendothelial system should be exploited to examine whether selective delivery of antiviral or immunomodulatory agents could be beneficial for the treatment of virus diseases. In this review we discuss the potential use of liposomes in the treatment of virus diseases, the targeting of liposome-encapsulated immunomodulators to macrophages in order to render these cells cytolytic for virus-infected cells, and the targeting of liposome-encapsulated antiviral drugs to macrophages to achieve direct suppression of virus replication with in these cells.

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References

    1. Glasgow L.A. Biology and pathogenesis of viral infections. In: Galasso G.J., Merigan T.C., Buchanan R.A., editors. Antiviral Agents and Viral Diseases of Man. Raven Press; New York: 1979. pp. 39–76.
    1. Vilček J. Fundamentals of virus structure and replication. In: Galasso G.J., Merigan T.C., Buchanan R.A., editors. Antiviral Agents and Viral Diseases of Man. Raven Press; New York: 1979. pp. 1–38.
    1. Smith R.A., Sidwell R.W., Robins R.K. Antiviral mechanisms of action. Ann. Rev. Pharmacol. Toxicol. 1980;20:259–284. - PubMed
    1. McIntosh K., Wilfert C., Cherneskey M., Plotkin S., Mattheis M.J. Summary on a workshop on new and useful techniques in rapid viral diagnosis. J. Infect. Dis. 1980;142:793–802. - PubMed
    1. Gregoriadis G., Neorungen D.E., Hunt R. Fate of liposome-associated agents injected into normal and tumor-bearing rodents. Life Sci. 1977;21:357–370. - PubMed

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