Cholesterol, stress, lifestyle, and coronary heart disease

Abstract

Because of the recent report by the Lipid Research Group showing that a lowering of total cholesterol and LDL cholesterol lowered mortality due to coronary heart disease (CHD) and other similar studies, there can no longer be any doubt that cholesterol is a causal factor in the development of CHD. Since total serum cholesterol and LDL cholesterol are produced by the body, those interested in the prevention of CHD must give greater attention to factors which are associated with raised endogenous cholesterol. The major factors are increased dietary and body fat, emotional arousal, and the inability of the liver to clear the serum of low density lipoprotein. The beneficial effect of exercise on lowering one's risk of CHD reported in the literature may be mediated by a rise in HDL cholesterol and/or weight loss. All patients should have their total cholesterol/HDL measured. Those with elevated serum cholesterols should be encouraged to eat a low saturated low fat diet, exercise, maintain proper weight and avoid undue distress. Cigarette smoking should be discouraged. Blood pressure elevations not responsive to diet and exercise should be treated with medication. Cholesterol elevations not responsive to life style change, should be treated with Cholestyramine.