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. 2024 Mar;24(1):220-227.
doi: 10.4314/ahs.v24i1.27.

Curosurf surfactant application on preterm babies with respiratory complications-health-economic benefits

Anna Mihaylova  1 , Kilova Kristina  2 , Petya Kasnakova  1 , Stanislav Gueorguiev  3 , Petkova Gueorguieva  4 , Desislava Bakova  1 , Nikoleta Parahuleva  5
Affiliations

Curosurf surfactant application on preterm babies with respiratory complications-health-economic benefits

Anna Mihaylova et al. Afr Health Sci. 2024 Mar.

Abstract

Background: The implementation of surfactant for respiratory syndrome approbates the therapy as a revolutionary method in intensive neonatal therapy and respiratory resuscitation. It is important to investigate the costs of this treatment.

Objective: The aim of the study is to analyze the data by the application of the surfactant Curosurf to preterm babies with respiratory complications and describe the treatment costs, healthcare resource utilization and evaluate economic benefits of surfactant use in the treatment of neonates with respiratory distress syndrome (RDS) and hyaline-membrane disease (HDM).

Methods: A retrospective survey was performed covering 167 babies based on respiratory complications due to preterm birth and the necessity to apply a surfactant therapy. A documentary method was implemented and for each patient, an individual research protocol was filled out - a questionnaire created specifically for the purposes of the study.

Results and discussion: An analysis of the data from the application of CUROSURF was made and the obtained therapeutic results were compared to expenditures for the therapy, short-term therapeutic effect, benefits and consequences of the therapy of preterm newborns with respiratory complications. The application of CUROSURF to babies with RDS resulted in the realization of net savings due to the elimination of the necessity of conducting several diagnostic and therapeutic procedures as well as their duration reduction of hospital stay, thus defining its health-economic benefits.

Conclusions: The models of evaluation of cost effectiveness reveal that the medicinal product is expensive but effective from the aspect of short-term therapeutic results.

Keywords: CUROSURF; health-economic benefits; preterm babies; respiratory complications; surfactant.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 2
Figure 2
Short-term therapeutic effects after surfactant administration
Figure 1
Figure 1
Study design
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