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Review
. 2024 Jun 26:2024:4904508.
doi: 10.1155/2024/4904508. eCollection 2024.

Tpeak-Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review

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Review

Tpeak-Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review

Irena Dykiert et al. Scientifica (Cairo). .

Abstract

Globally, cardiovascular diseases are still the leading cause of death. Numerous methods are used to diagnose cardiovascular pathologies; there is still a place for straightforward and noninvasive techniques, such as electrocardiogram (ECG). Depolarization and repolarization parameters, including QT interval and its derivatives, are well studied. However, the Tpeak-Tend interval is a novel and promising ECG marker with growing evidence for its potential role in predicting malignant arrhythmias. In this review, we discuss the association between the Tpeak-Tend interval and several cardiovascular diseases, including long QT syndrome, cardiomyopathies, heart failure, myocardial infarction, and obesity, which constitutes one of the risk factors for cardiovascular diseases.

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Conflict of interest statement

The authors declare that there are no conflicts of interest regarding the publication of this study.

Figures

Figure 1
Figure 1
ECG repolarization intervals: QT, JTpeak, and Tp-e.
Figure 2
Figure 2
PRISMA flowchart for study selection.
Figure 3
Figure 3
Tp-e interval: current state of knowledge summary.

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References

    1. Global health estimates. Leading causes of death. 2023. https://www.who.int/data/gho/data/themes/mortality-and-global-health-est... .
    1. Karaagac K., Yontar O. C., Tenekecioglu E., et al. Evaluation of Tp-Te interval and Tp-Te/QTc ratio in patients with coronary artery ectasia. International Journal of Clinical and Experimental Medicine . 2014;7(9):2865–2870. - PMC - PubMed
    1. Tse G., Yan B. P. Traditional and novel electrocardiographic conduction and repolarization markers of sudden cardiac death. EP Europace . 2017;19(5):712–721. doi: 10.1093/europace/euw280. - DOI - PubMed
    1. Yılmaz M., Kayançiçek H., Gözel N., et al. Spotlights on some electrocardiographic paradigms: how should we evaluate normal reference values of Tp–Te interval, Tp–Te dispersion and Tp–Te/QT ratio? Advances in Clinical and Experimental Medicine . 2020;29(9):1091–1099. doi: 10.17219/acem/117684. - DOI - PubMed
    1. Castro-Torres Y. Tp-e interval and Tp-e/QTc ratio: new choices for risk stratification of arrhythmic events in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology . 2017;17(6):p. 493. doi: 10.14744/anatoljcardiol.2017.7865. - DOI - PMC - PubMed

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