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. 1985 Jun;352(2):286-90.
doi: 10.1016/0165-3806(85)90116-6.

A marker of early amacrine cell development in rat retina

C J Barnstable, R Hofstein, K Akagawa

A marker of early amacrine cell development in rat retina

C J Barnstable et al. Brain Res. 1985 Jun.

Abstract

A monoclonal antibody, HPC-1, labels only amacrine and displaced amacrine cells in adult rat retina. Reactivity with displaced amacrine cells was demonstrated by double-label immunofluorescence with HPC-1 and ganglion cell-specific reagents. HPC-1 antibody reacts with a polypeptide of apparent molecular weight 35,000. HPC-1 antibody labels migrating amacrine cells in late embryonic retinas. The results define cell-specific gene expression in relation to migration of one subclass of CNS neurons.

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