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. 2023 Jul;62(Suppl2):104-109.
doi: 10.20471/acc.2023.62.s2.14.

THULIUM:YAG LASER ENUCLEATION OF THE PROSTATE (ThuLEP) - OUR EXPERIENCE IN 246 PATIENTS

Nikola Zebić  1 , Velimir Terzić  2   3 , Vinko Krajina  4   3
Affiliations

THULIUM:YAG LASER ENUCLEATION OF THE PROSTATE (ThuLEP) - OUR EXPERIENCE IN 246 PATIENTS

Nikola Zebić et al. Acta Clin Croat. 2023 Jul.

Abstract

New minimally invasive procedures to treat benign prostatic hyperplasia (BPH) have been developed in the last 20 years. With the introduction of laser enucleation techniques in prostate surgery, previous standard surgical procedures (open retropubic or transvesical adenectomy and transurethral resection of the prostate) have become less relevant, especially in case of very large prostates. The objective of this paper is to describe the experience and results of thulium:YAG laser application in BPH treatment in our department. In the last five years, 246 patients underwent thulium:YAG laser enucleation of the prostate (ThuLEP) due to BPH or lower urinary tract symptoms following complete urologic evaluation. The mean age of our patients was 73 (range 51-95) years and mean duration of surgery was 92 minutes. The mean weight of enucleated tissue was 73 grams. A low rate of intraoperative and early postoperative complications and short length of stay proved minimal invasiveness of this procedure, which results in significant improvements in urodynamic parameters and substantially reduces the post-void residual urine volume. The most important surgical and technical characteristics (enucleation and low-power laser application) make ThuLEP a safe and efficient surgical method not limited by the prostate volume. ThuLEP has a potential to displace the current standard surgical procedures to treat BPH.

Keywords: Benign prostatic hyperplasia; Minimally invasive surgery; Thulium:YAG laser.

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Figures

Fig. 1
Fig. 1
Prostatic tissue penetration depth.
See this image and copyright information in PMC

References

    1. Madersbacher S, Lackner J, Brössner C, Röhlich M, Stancik I, Willinger M, et al. Reoperation, myocardial infarction and mortality after transurethral and open prostatectomy: a nation-wide, long-term analysis of 23,123 cases. Eur Urol. 2005;47(4):499–504. 10.1016/j.eururo.2004.12.010 - DOI - PubMed
    1. Herrmann TR, Bach T, Imkamp F, Georgiou A, Burchardt M, Oelke M, et al. Thulium laser enucleation of the prostate (ThuLEP): transurethral anatomical prostatectomy with laser support. Introduction of a novel technique for the treatment of benign prostatic obstruction. World J Urol. 2010;28(1):45–51. 10.1007/s00345-009-0503-0 - DOI - PubMed
    1. Wolters M, Huusmann S, Oelke M, Kuczyk MA, Herrmann TR. Anatomical enucleation of the prostate with thulium:YAG support: redefinition of the surgical approach in two-lobe technique. Videourology (New Rochelle). 2016;30(6): 10.1089/vid.2016.0029 - DOI
    1. Kim YJ, Lee YH, Kwon JB, Cho SR, Kim JS. A novel one lobe technique of thulium laser enucleation of the prostate: ‘all-in-one’ technique. Korean J Urol. 2015;56(11):769–74. 10.4111/kju.2015.56.11.769 - DOI - PMC - PubMed
    1. Netsch C, Becker B, Tiburtius C, Moritz C, Venneri Becci A, Herrmann TR, et al. A prospective, randomized trial comparing thulium vapoenucleation with holmium laser enucleation of the prostate for the treatment of symptomatic benign prostatic obstruction: perioperative safety and efficacy. World J Urol. 2017;35(12):1913–21. 10.1007/s00345-017-2071-z - DOI - PubMed

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