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Review
. 2024 Sep 1;67(3):589-604.
doi: 10.1097/GRF.0000000000000881. Epub 2024 Jul 5.

Maternal Sepsis

Claudia Nieuwoudt  1 , Sarah E White, R Phillips Heine, Talla Motakef Widelock
Affiliations
Review

Maternal Sepsis

Claudia Nieuwoudt et al. Clin Obstet Gynecol. .

Abstract

Sepsis is the second leading cause of pregnancy-related mortality in the United States. Early recognition, treatment, and escalation of care for the obstetric patient affected by sepsis mitigate the risk of mortality and improve patient outcomes. In this article, we provide an overview of maternal sepsis and address topics of maternal pathophysiology, early warning signs, diagnostic criteria, early goal-directed therapy, and contemporary critical care practices. We also present an overview of common etiologies of maternal sepsis and suggested treatment approaches.

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References

    1. Maternal Mortality Rates in the United States, 2021. National Center for Health Statistics (U.S.); 2023. https://stacks.cdc.gov/view/cdc/124678/cdc_124678_DS1.pdf
    1. Prevention CfDCa. Pregnancy Mortality Surveillance System https://www.cdc.gov/reproductivehealth/maternal-mortality/pregnancy-mort...
    1. Organization WH. Statement on Maternal Sepsis. World Health Organization; 2023​​​​​​
    1. Lawton B, MacDonald EJ, Brown SA, et al. Preventability of severe acute maternal morbidity. Am J Obstet Gynecol. 2014;210:557.e1–6.
    1. Bauer ME, Lorenz RP, Bauer ST, et al. Maternal deaths due to sepsis in the state of Michigan, 1999-2006. Obstet Gynecol. 2015;126:747–752.