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. 1979 Jun 15;56(3):277-81.
doi: 10.1016/0014-2999(79)90184-5.

Nigrostriatal lesions enhance striatal 3H-apomorphine and 3H-spiroperidol binding

I Creese, S H Snyder

Nigrostriatal lesions enhance striatal 3H-apomorphine and 3H-spiroperidol binding

I Creese et al. Eur J Pharmacol. .

Abstract

Following unilateral 6-hydroxydopamine nigrostriatal lesions in rats, the binding of both 3H-apomorphine and 3H-spiroperidol in the striatum is increased. In rats with incomplete lesions or at early time points after lesion, binding is not significantly different from control levels.

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