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. 2024 Jul-Aug;37(4):458-465.
doi: 10.20524/aog.2024.0891. Epub 2024 Jun 14.

The growing trend of vascular intestinal disorder in young individuals: a 20-year analysis

Pojsakorn Danpanichkul  1   2 , Yatawee Kanjanakot  3 , Siwanart Kongarin  4 , Phuuwadith Wattanachayakul  5 , Chawin Lopimpisuth  6 , Sakditad Saowapa  2 , Nattanicha Chaisrimaneepan  2 , Priyata Dutta  7 , Yanfang Pang  8   9   10 , Kwanjit Duangsonk  8
Affiliations

The growing trend of vascular intestinal disorder in young individuals: a 20-year analysis

Pojsakorn Danpanichkul et al. Ann Gastroenterol. 2024 Jul-Aug.

Abstract

Background: Vascular intestinal disorder (VID) is a condition with a low incidence, but a high mortality risk. The increasing prevalence of substance abuse and metabolic syndrome among young individuals could impact the burden of VID. This study aimed to evaluate the impact of VID on young individuals.

Methods: Our study harnessed data from the Global Burden of Disease study, spanning 2000 to 2019. With this extensive dataset, we conducted a comprehensive analysis of the prevalence, mortality rates, and impact on disability-adjusted life years (DALYs) related to VID among young individuals aged 15 to 49 years.

Results: Globally, there were an estimated 32,628 cases, 3869 deaths, and 201,099 million DALYs attributed to VID in young individuals. Geographically, the regions of America had the highest burden of VID in young individuals. From 2000-2019, there was an increasing prevalence in all areas, with the most pronounced change observed in Southeast Asia (annual percentage change [APC] +2.17%, P<0.001). Over the study period, there was a more rapid increase in prevalence in males (APC +0.82%, P<0.001) than in females (APC +0.59%, P<0.001). Rates of death and DALYs declined in most regions, except for the Eastern Mediterranean region, where there was a slight increase (APC +0.85%, P<0.001 and 0.88%, P<0.001, respectively).

Conclusion: Over the past decade, the burden of VID in young individuals has been increasing, particularly in Southeast Asia and the Eastern Mediterranean region, necessitating immediate and inclusive measures to tackle the rising burden.

Keywords: Mesenteric ischemia; epidemiology; gastroenterology; vascular disease.

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Conflict of interest statement

Conflict of Interest: None

Figures

Figure 1
Figure 1
(A) The number of cases of vascular intestinal disorder (VID) in patients aged 15-49 years: cases in 2000 and 2019, stratified by World Health Organization (WHO) region. (B) Age-standardized prevalence rates attributable to VID in patients aged 15-49 in 2000 and 2019, stratified by WHO region. (C) The number of VID-related deaths in patients aged 15-49 in 2000 and 2019, stratified by the WHO region. (D) Age-standardized death rates attributable to VID in patients aged 15-49 in 2000 and 2019, stratified by WHO region. (E) The number of VID-related disabilities in patients aged 15-49 in 2000 and 2019, stratified by WHO region. (F) Age-standardized disability-adjusted life-years attributable to VID in patients aged 15-49 in 2000 and 2019, stratified by WHO region ASPR, age standardized prevalence rate; ASDR, age standardized death rate; ASDALYs, age standardized disability adjusted life years; DALYs, disability adjusted life years
Figure 2
Figure 2
(A) Age-standardized prevalence rates attributable to vascular intestinal disorder (VID) in patients aged 15-49 in 2000 and 2019, stratified by Sociodemographic Index (SDI). (B) Age-standardized death rates attributable to VID in patients aged 15-49 in 2000 and 2019, stratified by SDI. (C) Age-standardized disability-adjusted life years attributable to VID in patients aged 15-49 in 2000 and 2019, stratified by SDI ASPR, age standardized prevalence rate; ASDR, age standardized death rate; ASDALYs, age standardized disability adjusted life years; SDI, sociodemographic index
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