Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jun 5;19(2):202-209.
doi: 10.1055/s-0044-1787054. eCollection 2024 Jun.

The Prevalence of the Middle Clinoid Process: A Cross-Sectional Comparative Study in Patients with and without Pathology of the Sella Turcica

Suppaluk Anukulsampan  1 , Chottiwat Tansirisithikul  1 , Bunpot Sitthinamsuwan  1
Affiliations

The Prevalence of the Middle Clinoid Process: A Cross-Sectional Comparative Study in Patients with and without Pathology of the Sella Turcica

Suppaluk Anukulsampan et al. Asian J Neurosurg. .

Abstract

Background The middle clinoid process (MCP), particularly caroticoclinoid ring (CCR) type of the MCP, is an important part of the sphenoid bone for skull base surgery. Previous studies have shown a wide range of MCP prevalence affected by various factors. However, no study has investigated the association between the MCP and the presence of sellar lesions. Objectives The main aim of this study was to evaluate the prevalence of the MCP in the Thai population and factors associated with its presence. Materials and Methods We conducted a cross-sectional study on 400 sides from 200 patients (100 with and 100 without sellar lesions) using cranial computerized tomography scans. Demographic data and MCP characteristics were collected. The association between individual variables and the presence of the MCP was determined by univariate and multivariate analysis. Results The MCP was identified in 168 of 400 sides (42%). Patients with sellar lesions had a significantly lower prevalence of the MCP compared with normal controls (29.5% versus 54.5%, p < 0.001). Of all MCP only 6% were the CCR type. Univariate and multivariate analysis showed that the absence of the sellar lesion was the only factor significantly associated with presence of the MCP (odds ratio: 2.86; 95% confidence interval: 1.90-4.32; p < 0.001). Conclusion The prevalence of the MCP was relatively high in the Thai population, while the prevalence of the CCR was relatively low compared with previous studies. The absence of sellar lesions was the only factor associated with the presence of the MCP.

Keywords: caroticoclinoid ring; cranial computerized tomography; middle clinoid process; prevalence; skull base surgery.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
Bone window of cranial computed tomography showing the absence of middle clinoid process (arrowhead) in a patient with a pituitary adenoma in sagittal ( A ) and axial planes ( B ), and in a patient without sellar lesion in sagittal ( C ) and axial planes ( D ). ACP, anterior clinoid process; TS, tuberculum sellae.
Fig. 2
Fig. 2
Bone window of cranial computed tomography showing the incomplete type of MCP in a patient with a pituitary adenoma in sagittal ( A ) and axial planes ( B ), and in a patient without sellar lesion in sagittal ( C ) and axial planes ( D ). ACP, anterior clinoid process; MCP, middle clinoid process; TS, tuberculum sellae.
Fig. 3
Fig. 3
Bone window of cranial computed tomography showing CCR (complete type of middle clinoid process) in a patient with pituitary adenoma in sagittal ( A ) and axial planes ( B ), and in a patient without sellar lesion in sagittal ( C ) and axial planes ( D ). ACP, anterior clinoid process; CCR, caroticoclinoid ring; TS, tuberculum sellae.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Inoue T, Rhoton A L, Jr, Theele D, Barry M E. Surgical approaches to the cavernous sinus: a microsurgical study. Neurosurgery. 1990;26(06):903–932. - PubMed
    1. Fernandez-Miranda J C, Tormenti M, Latorre F, Gardner P, Snyderman C.Endoscopic endonasal middle clinoidectomy: anatomic, radiological, and technical note Neurosurgery 201271(2, suppl Operative):ons233–ons239. - PubMed
    1. Sharma A, Rieth G E, Tanenbaum J E et al.A morphometric survey of the parasellar region in more than 2700 skulls: emphasis on the middle clinoid process variants and implications in endoscopic and microsurgical approaches. J Neurosurg. 2018;129(01):60–70. - PubMed
    1. Miller C, Chamoun R, Beahm D. Morphometric analysis of the middle clinoid process using maxillofacial computed tomography scans. Oper Neurosurg (Hagerstown) 2017;13(01):124–130. - PubMed
    1. Keyes J EL. Observations on four thousand optic foramina in human skulls of known origin. Arch Ophthalmol. 1935;13(04):538–568.

LinkOut - more resources