Comprehensive Discussions on KIT ATP-Binding Pocket/Activation Loop Mutations in Ripretinib Resistance

Affiliations

¹ Yanzhe Xia, MSc, Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; and Xinhua Zhang, MD, Center for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Comment

Yanzhe Xia et al. J Clin Oncol. 2024.

. 2024 Sep 20;42(27):3259.

doi: 10.1200/JCO.24.00673. Epub 2024 Jul 8.

¹ Yanzhe Xia, MSc, Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; and Xinhua Zhang, MD, Center for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

No abstract available

Comment in

Reply to Y. Xia et al.
Bauer S, Fletcher JA, Rauh D, Falkenhorst J, Mühlenberg T. Bauer S, et al. J Clin Oncol. 2024 Sep 20;42(27):3260-3261. doi: 10.1200/JCO.24.00942. Epub 2024 Jul 8. J Clin Oncol. 2024. PMID: 38976807 No abstract available.

KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape.
Mühlenberg T, Falkenhorst J, Schulz T, Fletcher BS, Teuber A, Krzeciesa D, Klooster I, Lundberg M, Wilson L, Lategahn J, von Mehren M, Grunewald S, Tüns AI, Wardelmann E, Sicklick JK, Brahmi M, Serrano C, Schildhaus HU, Sievers S, Treckmann J, Heinrich MC, Raut CP, Ou WB, Marino-Enriquez A, George S, Rauh D, Fletcher JA, Bauer S. Mühlenberg T, et al. J Clin Oncol. 2024 Apr 20;42(12):1439-1449. doi: 10.1200/JCO.23.01197. Epub 2024 Feb 26. J Clin Oncol. 2024. PMID: 38408285 Free PMC article.