Compliance with ethical standards Guarantor The scientific guarantor of this publication is E.C. Conflict of interest The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. Statistics and biometry No complex statistical methods were necessary for this commentary. Informed consent Written informed consent was not required. Ethical approval Institutional Review Board approval was not required. Study subjects or cohorts overlap Not applicable. Methodology Commentary