Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Sep;103(3):410-8.

R46 and pKM101 plasmid-mediated resistance to ionizing radiation in Escherichia coli

I Francia, S Hernadi, M Szabolcs, F Hernadi
  • PMID: 3898204

R46 and pKM101 plasmid-mediated resistance to ionizing radiation in Escherichia coli

I Francia et al. Radiat Res. 1985 Sep.

Abstract

The ability of the R46 R factor and its derivative pKM101 to modify sensitivity to 60Co gamma radiation was studied. In Escherichia coli K12 both plasmids enhanced bacterial survival after 60Co gamma irradiation. This effect was dependent on recA+ genotype but not on recB+, recB+ recC+, and recF+ genotypes. 5-Fluorouracil eliminated the R46 R factor from the parent and its rec- mutant strains. These strains lost not only the antibiotic resistance coded for R46 R factor but their radioresistance as well.

PubMed Disclaimer

Substances