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Comparative Study
. 1979:7 Suppl 5:S443-5.
doi: 10.1007/BF01659767.

Efficacy of bacampicillin and ampicillin in experimental pyelonephritis in the rat

W Ritzerfeld
Comparative Study

Efficacy of bacampicillin and ampicillin in experimental pyelonephritis in the rat

W Ritzerfeld. Infection. 1979.

Abstract

Bacampicillin and ampicillin were tested and compared with each other in a model of acute, obstructive pyelonephritis in the rat. The compounds were administered orally at five dose levels ranging from 50 mg/kg to 150 mg/kg. Bacampicillin was found to have a greater therapeutic activity than ampicillin, particulary at the higher doses, indicating that its improved absorption properties make it a therapeutically more effective compound than ampicillin.

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References

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    1. Antimicrob Agents Chemother. 1975 Nov;8(5):518-25 - PubMed
    1. Zentralbl Bakteriol Orig A. 1974;227(1-4):298-305 - PubMed

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