Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024 May 27;9(5):605-606.
doi: 10.1016/j.jacbts.2024.03.006. eCollection 2024 May.

Dysregulation of IL-6/MCP-1/STAT3 Axis: A Promising Therapeutic Postinfarction Inflammation Strategy?

Andreas Mitsis  1 , Stergios Tzikas  2 , George Kassimis  3
Affiliations
Editorial

Dysregulation of IL-6/MCP-1/STAT3 Axis: A Promising Therapeutic Postinfarction Inflammation Strategy?

Andreas Mitsis et al. JACC Basic Transl Sci. .
No abstract available

Keywords: IL-6; MCP-1; STAT3; inflammation; macrophages; myocardial infarction.

PubMed Disclaimer

Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
See this image and copyright information in PMC

Comment on

  • doi: 10.1016/j.jacbts.2024.01.019

References

    1. Mitsis A., Kadoglou N.P.E., Lambadiari V., et al. Prognostic role of inflammatory cytokines and novel adipokines in acute myocardial infarction: an updated and comprehensive review. Cytokine. 2022;153 - PubMed
    1. Ridker P.M., Lüscher T.F. Anti-inflammatory therapies for cardiovascular disease. Eur Heart J. 2014;35:1782–1791. - PMC - PubMed
    1. Tøllefsen I.M., Shetelig C., Seljeflot I., Eritsland J., Hoffmann P., Andersen G.Ø. High levels of interleukin-6 are associated with final infarct size and adverse clinical events in patients with STEMI. Open Heart. 2021;8 - PMC - PubMed
    1. Broch K., Anstensrud A.K., Woxholt S., et al. Randomized trial of interleukin-6 receptor inhibition in patients with acute ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2021;77:1845–1855. - PubMed
    1. de Lemos J.A., Morrow D.A., Sabatine M.S., et al. Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes. Circulation. 2003;107:690–695. - PubMed

Publication types

LinkOut - more resources