Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Jan;40(1):69-84.
doi: 10.1007/s00467-024-06444-z. Epub 2024 Jul 10.

Nutritional management of the child with chronic kidney disease and on dialysis

Affiliations
Review

Nutritional management of the child with chronic kidney disease and on dialysis

Vanessa Shaw et al. Pediatr Nephrol. 2025 Jan.

Abstract

While it is widely accepted that the nutritional management of the infant with chronic kidney disease (CKD) is paramount to achieve normal growth and development, nutritional management is also of importance beyond 1 year of age, particularly in toddlers, to support the delayed infantile stage of growth that may extend to 2-3 years of age. Puberty is also a vulnerable period when nutritional needs are higher to support the expected growth spurt. Inadequate nutritional intake throughout childhood can result in failure to achieve full adult height potential, and there is an increased risk for abnormal neurodevelopment. Conversely, the rising prevalence of overweight and obesity among children with CKD underscores the necessity for effective nutritional strategies to mitigate the risk of metabolic syndrome that is not confined to the post-transplant population. Nutritional management is of primary importance in improving metabolic equilibrium and reducing CKD-related imbalances, particularly as the range of foods eaten by the child widens as they get older (including increased consumption of processed foods), and as CKD progresses. The aim of this review is to integrate the Pediatric Renal Nutrition Taskforce (PRNT) clinical practice recommendations (CPRs) for children (1-18 years) with CKD stages 2-5 and on dialysis (CKD2-5D). We provide a holistic approach to the overall nutritional management of the toddler, child, and young person. Collaboration between physicians and pediatric kidney dietitians is strongly advised to ensure comprehensive and tailored nutritional care for children with CKD, ultimately optimizing their growth and development.

Keywords: Child; Chronic kidney disease; Energy; Growth; Nutrition; Phosphate; Protein.

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflict of interest: The authors declare no competing interests. Disclaimer: The Pediatric Renal Nutrition Taskforce wishes to confirm that Vitaflo has not influenced the content of this Educational Review.

Figures

None
A higher resolution version of the Graphical abstract is available as Supplementary information
Fig. 1
Fig. 1
Guide to the nutrient content of foods. Caution: when advising the individual child consider first their blood biochemistry, diet as a whole, appetite and food preferences, portion sizes, food availability, and family’s cooking skills before restricting any nutrients

Similar articles

Cited by

References

    1. Rees L, Jones H (2013) Nutritional management and growth in children with chronic kidney disease. Pediatr Nephrol 28:527–536. 10.1007/s00467-012-2258-x - PubMed
    1. Greenbaum LA, Muñoz A, Schneider MF, Kaskel FJ, Askenazi DJ, Jenkins R, Hotchkiss H, Moxey-Mims M, Furth SL, Warady BA (2011) The association between abnormal birth history and growth in children with CKD. Clin J Am Soc Nephrol 6:14–21. 10.2215/CJN.08481109 - PMC - PubMed
    1. Karlberg J, Schaefer F, Hennicke M, Wingen A-M, Rigden S, Mehls O, European Study Group for Nutritional Treatment of Chronic Renal Failure in Childhood (1995) Early age-dependent growth impairment in chronic renal failure. Pediatr Nephrol 10:283–287. 10.1007/BF00866761 - PubMed
    1. Shaw V, Anderson C, Desloovere A, Greenbaum LA, Haffner D, Nelms CL, Paglialonga F, Polderman N, Qizalbash L, Renken-Terhaerdt J, Stabouli S, Tuokkola J, Vande Walle J, Warady BA, Shroff R (2023) Nutritional management of the infant with chronic kidney disease stages 2–5 and on dialysis. Pediatr Nephrol 38:87–103. 10.1007/s00467-022-05529-x - PMC - PubMed
    1. Chandy CJ, Black MM, Nelson CA (2017) Neurodevelopment: the impact of nutrition and inflammation during early to middle childhood in low-resource settings. Pediatrics 139(Suppl 1):S59–S71. 10.1542/peds.2016-2828H - PMC - PubMed

LinkOut - more resources