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. 2024 Feb 23;38(2):138-143.
doi: 10.4103/sjopt.sjopt_182_23. eCollection 2024 Apr-Jun.

Role of optical coherence tomography angiography in the evaluation of peripheral ischemia in retinal vein occlusion

Emanuele Crincoli  1 , Riccardo Sacconi  1 , Andrea Servillo  1 , Beatrice Tombolini  1 , Giuseppe Querques  1
Affiliations

Role of optical coherence tomography angiography in the evaluation of peripheral ischemia in retinal vein occlusion

Emanuele Crincoli et al. Saudi J Ophthalmol. .

Abstract

In the last decade, optical coherence tomography angiography (OCTA) has become part of the clinical management of retinal vein occlusion (RVO), proving in itself a useful technique for both the prediction of visual acuity (VA) outcomes and the risk of complications. In fact, OCTA has been proven a valid imaging technique in detailed assessment of foveal and parafoveal microvascular status in both acute and chronic RVO. Quantitative OCTA data have shown a significant correlation not only with final VA but also with the extension of peripheral ischemia, which represents a major risk factor for macular edema recurrence and neovascularization onset. Finally, wide-field OCTA represents a promising noninvasive technique for the assessment of peripheral ischemia. The aim of this review is to report the main literature findings about microvascular changes and clinical applications of OCTA in the context of RVO-induced peripheral ischemia.

Keywords: Deep capillary plexus; optical coherence tomography angiography; peripheral ischemia; retinal vein occlusion; wide-field optical coherence tomography angiography.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Early phase ultrawide field fluorescein angiography (UWF FA). (b) Mid-phase UWF FA. (c) Late phase UWF FA. (d) Pseudocolor UWF. (e) Macular enface angiogram of the superficial capillary plexus. (f) Macular enface angiogram of the deep capillary plexus of a case of ischemic retinal vein occlusion 2 weeks after the onset of symptoms. Microvascular rarefaction prevalently in deep capillary plexus and watershed area congestion can be noted in optical coherence tomography angiography images
Figure 2
Figure 2
(a) Cross-sectional fovea crossing optical coherence tomography angiography. (b) Ultrawide (UWF) pseudo color fundus image. (c) Early phase UWF Fluorescein angiography (UWF FA). (d) Mid-phase UWF FA. (e) Late phase UWF FA. (f) UWF angiogram of the superficial capillary plexus. (g) UWF angiogram of the deep capillary plexus of a case of ischemic retinal vein occlusion 1 year after the event. Ischemic areas clearly colocalize in fluorescein angiography and optical coherence tomography angiography images
See this image and copyright information in PMC

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