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Meta-Analysis
. 2024 Jul 11;39(1):179.
doi: 10.1007/s10103-024-04111-1.

High-intensity versus low-level laser in musculoskeletal disorders

Affiliations
Meta-Analysis

High-intensity versus low-level laser in musculoskeletal disorders

Marwa Shafiek Saleh et al. Lasers Med Sci. .

Abstract

Purpose: To evaluate the current evidence comparing low level to high level laser therapy to reveal any superiorities in the treatment of musculoskeletal disorders.

Methods: Five databases were searched till September 2022 to obtain relevant RCTs comparing high intensity and low-level laser therapies in the management of musculoskeletal disorders. Two authors assessed the methodological quality of the included studies using the Physiotherapy Evidence Database scale and meta-analysis was conducted for studies that showed homogeneity.

Results: Twelve articles were included in this systematic review with a total population of 704 participants across various musculoskeletal pathologies including tennis elbow, carpal tunnel syndrome, chronic non-specific low back pain, knee arthritis, plantar fasciitis, and subacromial impingement. There were no statistical differences between the two interventions in pain, electrophysiological parameters, level of disability, quality of life, postural sway or pressure algometer, however, Low level laser therapy showed superiority in increasing grip strength compared to high intensity laser therapy while results were significant in favour of high intensity laser therapy regarding long head of biceps diameter and cross sectional area, supraspinatus thickness and echogenicity and acromio-humeral distance.

Conclusion: The current literature suggests no superiority of both types of laser therapy in musculoskeletal disorders, however, more RCTs with larger sample size are required to reach a definitive conclusion regarding the superiority of either form of laser therapy in musculoskeletal disorders.

Keywords: Arthritis; Back pain; Carpal tunnel syndrome; HILT; High intensity; Impingement; LLLT; Laser; Low-level; Musculoskeletal.

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Conflict of interest statement

No commercial party having a direct financial interest in the results of the research supporting this article has conferred or will confer a benefit on the authors or any organization with which the authors are associated.

Figures

Fig. 1
Fig. 1
PRISMA flowchart of studies search and selection
Fig. 2
Fig. 2
Forest plot of comparison: between HILT and LLLT, outcome pain
Fig. 3
Fig. 3
Forest plot of comparison: between HILT and LLLT, outcome grip strength

References

    1. Girgis CM, Mokbel N, Digirolamo DJ (2014) Therapies for musculoskeletal disease: can we treat two birds with one stone? Curr Osteoporos Rep 12(2):142–153 - DOI - PMC - PubMed
    1. Pitsillides AA, Inflammation Protocols. Methods In, Volume 225 (2003) Molecular Biology,. Edited by P. G. Winyard and D. A. Willoughby. $99.50. Humana Press, Totowa, NJ, 380 pages. ISBN 0-86903-970-6. Rheumatology. 2004;43(6):814–814
    1. Williams A, Kamper SJ, Wiggers JH, O’Brien KM, Lee H, Wolfenden L et al (2018) Musculoskeletal conditions may increase the risk of chronic disease: a systematic review and meta-analysis of cohort studies. BMC Med 16(1):167 - DOI - PMC - PubMed
    1. Cieza A, Causey K, Kamenov K, Hanson SW, Chatterji S, Vos T (2021) Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the global burden of Disease Study 2019. Lancet 396(10267):2006–2017 - DOI - PMC - PubMed
    1. Babatunde OO, Jordan JL, Van der Windt DA, Hill JC, Foster NE, Protheroe J (2017) Effective treatment options for musculoskeletal pain in primary care: a systematic overview of current evidence. PLoS ONE 12(6):e0178621 - DOI - PMC - PubMed

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